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IGCSE · Cambridge (CIE) · 0970

Describe skin and nose hairs as body defences

Explain physical barriers before discussing responses inside the body.

Section 10.1 · Diseases and immunity

Disease and immunity pathway · 0970 (9–1) · 10.1
Exam scope and assessment notes

Core and Extended · Biology 0970, 2026–2028. Use the stated specimen features and evidence. Diagrams are schematic. Written practice is self-checked; human subject-teacher review, supervised practical competence and cumulative assessment remain pending. Cambridge states that IGCSE 0970 has the same subject content as IGCSE 0610, with 9–1 grading. This StudyForA pathway maps the 2026–2028 syllabus only. This 9–1 graded qualification is available only in a limited number of administrative zones. Confirm that your centre can enter you for this code and exam series with Cambridge International. Cambridge has published a separate syllabus for 2029. StudyForA has not reconciled that version yet; this page supports exams in 2026, 2027 and 2028 only.

Before you begin

  • Recall clotting and pathogen entry.

Work on paper. Try each question before revealing help, and explain why your method works.

Quick readiness check

What is a physical barrier?

What you will learn

  • A barrier can reduce entry
  • Nose hairs act at an air entrance
Outside → barrier → internal tissue: an intact barrier limits entry but does not imply a sterile surface.Describe skin and nosehairs as body defencesSkinPhysical entry barrierNose hairsTrap some particlesDamageCan open an entry route
Outside → barrier → internal tissue: an intact barrier limits entry but does not imply a sterile surface. Original teaching model.

A barrier can reduce entry

Skin forms a physical barrier between the external environment and internal tissues. An intact outer surface makes entry harder for many pathogens; a wound can provide an entry route that was previously blocked. Protection is a biological barrier function rather than a claim that the skin surface contains no microorganisms.

The skin does not need to recognise the exact antigen of every pathogen to act as a barrier. Distinguish this general first defence from later specific antibody responses. A clot at damaged skin can help seal the entry route, linking this lesson with the earlier blood-clotting sequence.

Nose hairs act at an air entrance

Hairs in the nose help trap particles, including particles carrying pathogens, before they move deeper into the breathing passages. Their position matters: they act near an entrance, not by producing antibodies in the lungs or sterilising all inhaled air. Some particles can still pass these defences.

For a structural explanation name both the feature and its effect: intact skin limits entry into tissues, while nose hairs trap some incoming particles. Do not claim that nose hairs directly kill every pathogen. Later lessons add mucus and white-cell action, showing that several defences can cooperate rather than one being perfect.

Pause and explain

What do nose hairs do in this syllabus description?

Put the idea to work

Worked example

A supplied wound breaks an intact skin barrier. Explain why pathogen entry may become easier.

Show the worked solution
  1. Skin normally separates the outside from internal tissue.
  2. The damage interrupts that barrier.

Answer The wound opens a route through the physical skin barrier into internal tissues.

Try a topic test

Choose Easy, Normal or Difficult. Save your answers and open worked review after finishing.

Test this topic →

From guided practice to a new situation

Write your answer and reasoning first. Use a hint only if you are stuck. The model solution is for self-checking; your written work is not automatically marked.

1 · Guided

Give one defence function of intact skin and one of nose hairs.

Give me a hint

State effects rather than only names.

Compare my reasoning
  1. Skin restricts entry into tissue.
  2. Hairs trap some incoming particles.

Skin acts as a physical barrier; nose hairs trap some particles that may carry pathogens.

Look for these in your work

  • Explain skin
  • Explain nose hairs
2 · Independent

Distinguish a skin barrier from antibody specificity.

Give me a hint

One blocks entry; one recognises matching antigens.

Compare my reasoning
  1. Skin does not require a particular antigen match for its barrier action.
  2. Antibodies bind specific complementary antigens.

Skin provides a general physical entry barrier; antibody binding depends on a specific matching antigen.

Look for these in your work

  • Differentiate mechanisms
  • Retain specificity
3 · Transfer

A student says that microbes on skin prove the skin has no defence role. Evaluate.

Give me a hint

Surface presence and tissue entry differ.

Compare my reasoning
  1. Microorganisms can be on the outside.
  2. Intact skin can still limit their entry into internal tissues.

The claim is wrong: surface microbes do not remove the intact skin’s physical barrier function.

Look for these in your work

  • Separate surface and inside
  • Use the barrier mechanism

Common mistakes

  • Calling skin an antibody.
  • Saying nose hairs sterilise all air.
Recall without your notes

What can you explain now?

What do nose hairs do in this syllabus description?

Compare with the explanation

Trap some incoming particles

Particles may carry pathogens.

After trying it yourself, choose your next review. This is your self-assessment.

Your review choice appears on Today. Sign in to sync it across devices.

Make it stick

Explain two structural defences and why neither requires sterile surroundings.

If you needed the solution, close it and solve the problem again from a blank page. A correct answer is stronger when you can explain the reason for each step.

Keep learning Biology (9-1)

Course scope and assessment

780 sequenced lessons provide 2340 guided, independent and application problems in characteristics, classification, cells, organisation, specimen size, membrane transport, biological molecules, enzymes, plant and human nutrition, plant transport, circulatory systems, the heart, blood vessels, blood, disease transmission, body defences, immunity, gas exchange in humans, respiration energy uses and investigations, aerobic respiration, anaerobic respiration and recovery, excretion in humans, coordination and response, sense organs, hormones, homeostasis, tropic responses, drugs, asexual reproduction, sexual reproduction, sexual reproduction in plants, sexual reproduction in humans, sex hormones in humans, sexually transmitted infections, chromosomes, genes and proteins, mitosis, meiosis, monohybrid inheritance, variation, adaptive features, selection, energy flow, food chains and webs, nutrient cycles, population, community, ecosystem, population-growth phases, food supply, habitat destruction, pollution, conservation, biotechnology and genetic modification. 61 of 61 syllabus sections have linked teaching and staged practice. The earlier inheritance overview remains introductory, and the monohybrid pathway develops the relevant Core and Supplement requirements. This is not full programme completion or guaranteed exam readiness. Written practice is self-checked. This is the separate 9–1 qualification 0970; Cambridge states that its 2026–2028 subject content is otherwise the same as 0610. This 9–1 graded qualification is available only in a limited number of administrative zones. Confirm that your centre can enter you for this code and exam series with Cambridge International. The 2029 syllabus is separately published at https://www.cambridgeinternational.org/Images/764352-2029-syllabus.pdf and is not yet mapped here. This course supports exams in 2026, 2027 and 2028 only.

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Original teaching content and links to official sources. Check your exam year and qualification before using a resource.