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IGCSE · Cambridge (CIE) · 0973

Explain the role of mitosis in growth of multicellular organisms

Completed mitotic cell cycles can increase cell number during growth. The invented one-cell lineage doubles to eight after three stated rounds, adding seven cells.

Section B16.2 · Cell division

Cell division · Cambridge IGCSE 0973 · B16.2
Exam scope and assessment notes

Mapped to the named 0973 section using teaching from the corresponding single-science course. A 0973-specific review of every Core and Supplement objective is still in progress. Written practice is self-checked; it does not demonstrate supervised laboratory competence or award an official Cambridge grade. This qualification reports two grades on the 9–1 scale; confirm the entry route for your zone and exam series.

Before you begin

  • Recall chromosomes, genes, chromosome sets, selective gene expression and the distinction between a nucleus and a whole cell.

Work on paper. Try each question before revealing help, and explain why your method works.

Quick readiness check

How does normal completed mitotic division contribute to growth?

What you will learn

  • Connect growth with increased cell number
  • Keep growth models conditional

Original teaching model. Counts and records are stipulated; drawings are schematic.

Explain the role of mitosis in growth of multicellular organismsCompleted mitotic cell cycles can increase cell number during growth. The invented one-cell lineage doubles to eight after three stated rounds, adding seven cells.RoleMore cells contribute tomulticellular growthModel rounds0, 1, 2 and 3Model totals1, 2, 4 and 8 cellsLimitNo timing or universal growth-rateprediction
Completed mitotic cell cycles can increase cell number during growth. The invented one-cell lineage doubles to eight after three stated rounds, adding seven cells.
Division, chromosome count and cell-state key
FeatureMeaning
RoleMore cells contribute to multicellular growth
Model rounds0, 1, 2 and 3
Model totals1, 2, 4 and 8 cells
LimitNo timing or universal growth-rate prediction

Connect growth with increased cell number

Mitosis contributes to growth by allowing dividing cells to produce daughter cells with the same genetic information. After normal nuclear division and subsequent cell division, one cell gives two, increasing the cell number by one. In a growing multicellular organism, many such events can build tissues containing more cells while preserving the chromosome complement in each product.

Growth of an organism is not explained only by mitosis. Cells may also enlarge, synthesise material and become specialised, and tissues must organise those products. A cell increasing its volume is not itself evidence that mitosis occurred. To explain the specified mitotic contribution, connect complete division with more cells rather than treating every increase in mass as a nuclear event.

Keep growth models conditional

An invented lineage starts with one cell and states that every cell completes division once per round, with no loss. Its counts are one, two, four and eight across rounds zero to three. These numbers describe the stipulated pattern, not the timing or growth rate of an actual embryo, plant or tissue. Different cells need not divide together or at a constant rate.

For this model, three rounds are not three individual divisions. The successive rounds contain one, two and four completed division events, adding seven cells to the original one. Label a round, an event, a total population and a net increase separately. Such arithmetic is useful only when the biological assumptions are supplied; normal mitosis does not imply unlimited exponential growth.

Sources for this lesson

Pause and explain

One starting cell undergoes three stipulated doubling rounds. What is the final count?

Put the idea to work

Worked example

One cell completes three whole-population rounds with no loss. What is the final count?

Show the worked solution
  1. Double at each stated round.
  2. Distinguish total from increase.

Answer The count is eight cells, a net increase of seven.

Try a topic test

Choose Easy, Normal or Difficult. Save your answers and open worked review after finishing.

Test this topic →

From guided practice to a new situation

Write your answer and reasoning first. Use a hint only if you are stuck. The model solution is for self-checking; your written work is not automatically marked.

1 · Guided

Explain the mitotic contribution to multicellular growth.

Give me a hint

Connect nuclear division with completed daughter cells.

Compare my reasoning
  1. Describe genetic information preserved in daughter nuclei.
  2. Connect subsequent cell division with more cells.

Normal mitosis followed by cell division produces additional cells with the same genetic information, contributing to growth.

Look for these in your work

  • Preserve the chromosome information
  • Explain increased cell number
2 · Independent

One cell completes three synchronous no-loss rounds. Calculate the final total and net increase.

Give me a hint

Use the sequence one, two, four, eight.

Compare my reasoning
  1. Double three times.
  2. Subtract the initial cell from the final total.

The final total is eight cells and the net increase is seven cells.

Look for these in your work

  • State the doubling assumptions
  • Separate total and increase
3 · Transfer

A tissue gains mass, but no cell-count or nuclear-division evidence is supplied. Can its mass change alone establish mitosis?

Give me a hint

Consider cell enlargement and synthesis.

Compare my reasoning
  1. Identify the observed mass change.
  2. State that division evidence is missing.

No. Increased mass can involve enlargement or synthesis; cell-number and nuclear-division evidence are needed to establish the mitotic contribution.

Look for these in your work

  • Use the observed quantity
  • Avoid an unsupported mechanism claim

Common mistakes

  • Cell enlargement is not itself mitosis.
  • Synchronous no-loss doubling is a stated model, not a universal growth rate.
Recall without your notes

What can you explain now?

One starting cell undergoes three stipulated doubling rounds. What is the final count?

Compare with the explanation

Eight cells

The counts are one, two, four and eight.

After trying it yourself, choose your next review. This is your self-assessment.

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Make it stick

Without your notes, connect growth with increased cell number and keep growth models conditional. Distinguish nuclear division, chromosome copies and completed daughter cells before opening the solutions.

If you needed the solution, close it and solve the problem again from a blank page. A correct answer is stronger when you can explain the reason for each step.

Keep learning Sciences — Co-ordinated (9-1)

Course scope and assessment

This 9–1 pathway maps all 152 detailed subject-content sections in the published 0973 syllabus for exams in 2028 and 2029. The course map follows the same 2028–2029 section codes as Cambridge's A*–G 0654 syllabus, while keeping 0973's grading and entry rules separate. It adapts lessons from the related single-science courses and excludes clear single-science-only topics. A 0973-specific objective-by-objective review, Core/Supplement audit, human subject-teacher review, supervised laboratory experience and cumulative assessment remain in progress. Written practice is self-checked and does not predict an official grade. The separate 2025–2027 syllabus has not been reconciled here. Cambridge lists 0973 only in a limited number of administrative zones: June in zone 3 and centres in Oman and the UAE; November in zone 3 only. Confirm entry with your centre.

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