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IGCSE · Cambridge (CIE) · 0973

Identify lymphocytes and phagocytes in diagrams

Use nucleus shape and cytoplasm to distinguish two white-cell examples.

Section B9.4 · Blood

Blood · Cambridge IGCSE 0973 · B9.4
Exam scope and assessment notes

Mapped to the named 0973 section using teaching from the corresponding single-science course. A 0973-specific review of every Core and Supplement objective is still in progress. Written practice is self-checked; it does not demonstrate supervised laboratory competence or award an official Cambridge grade. This qualification reports two grades on the 9–1 scale; confirm the entry route for your zone and exam series.

Before you begin

  • Recall white-cell diagram identification.

Work on paper. Try each question before revealing help, and explain why your method works.

Quick readiness check

Which two diagrams are white cells?

What you will learn

  • Recognise the lymphocyte example
  • Recognise a phagocyte example without overgeneralising
B lymphocyte: large round nucleus, narrow cytoplasm rim. C neutrophil phagocyte: lobed nucleus. Other phagocyte types can differ; no actual scale is implied.Two white-cell examplesA: mature red cellCentral pallor; no nucleusB: lymphocyteLarge round nucleusC: phagocyte (neutrophil)Lobed nucleus; cytoplasm
B lymphocyte: large round nucleus, narrow cytoplasm rim. C neutrophil phagocyte: lobed nucleus. Other phagocyte types can differ; no actual scale is implied. Original schematic, not to scale.

Recognise the lymphocyte example

In the original comparison, B is a lymphocyte. Its large round nucleus occupies much of the cell, leaving a relatively narrow rim of cytoplasm. That combination supports this example’s identity; do not describe the nucleus as the whole cell or mistake the thin rim for plasma outside it.

A and C supply comparison: A is a mature red cell without a nucleus, and C is a neutrophil, a phagocyte type. The drawn colours are conventions. White-cell identification depends on the supplied morphology and specimen context, not merely being a purple circle.

Recognise a phagocyte example without overgeneralising

C shows a segmented or lobed nucleus and more visible surrounding cytoplasm. These features are characteristic of the neutrophil example used here. Phagocytes engulf pathogens by phagocytosis. Other phagocyte types can have different nucleus shapes, so avoid claiming every phagocyte must look exactly like this drawing.

The syllabus asks learners to recognise lymphocytes and phagocytes in diagrams and photomicrographs. Start with this simplified comparison, then move to the source-confirmed microscope examples. A still diagram of a phagocyte is not itself evidence that engulfing is occurring at that instant; identification and active-function evidence are separate.

Sources for this lesson

Pause and explain

Which identification matches B and C?

Put the idea to work

Worked example

Name B and C and justify each using its nucleus.

Show the worked solution
  1. B has a large round nucleus with a narrow cytoplasm rim.
  2. C is the neutrophil example with a lobed nucleus.

Answer B lymphocyte; C phagocyte (neutrophil example). Their nucleus shapes support the distinction.

Try a topic test

Choose Easy, Normal or Difficult. Save your answers and open worked review after finishing.

Test this topic →

From guided practice to a new situation

Write your answer and reasoning first. Use a hint only if you are stuck. The model solution is for self-checking; your written work is not automatically marked.

1 · Guided

Identify B and give two supporting features.

Give me a hint

Look at the round nucleus and remaining cytoplasm.

Compare my reasoning
  1. The nucleus is large and round.
  2. A relatively narrow cytoplasm rim remains.

B lymphocyte: large round nucleus and narrow cytoplasm rim.

Look for these in your work

  • Name lymphocyte
  • Use both structural features
2 · Independent

Identify C and state the example’s nucleus feature.

Give me a hint

The drawing is a neutrophil example.

Compare my reasoning
  1. Its nucleus is segmented or lobed.
  2. Neutrophils are phagocytes.

C phagocyte, represented by a neutrophil with a lobed nucleus.

Look for these in your work

  • Name phagocyte
  • Qualify the neutrophil example
3 · Transfer

A different phagocyte has a kidney-shaped nucleus. Must it be rejected because C is lobed?

Give me a hint

One example is not the entire group.

Compare my reasoning
  1. Phagocyte types can differ in nuclear shape.
  2. Use source identity and full morphology for the new specimen.

No; the neutrophil drawing does not define every phagocyte shape. Use the new specimen’s verified identity and features.

Look for these in your work

  • Avoid an absolute shape rule
  • Use specimen evidence

Common mistakes

  • Calling the lymphocyte nucleus the entire cell.
  • Claiming all phagocyte types have identical lobed nuclei.
Recall without your notes

What can you explain now?

Which identification matches B and C?

Compare with the explanation

B lymphocyte; C phagocyte example

B has a large round nucleus; C a lobed one.

After trying it yourself, choose your next review. This is your self-assessment.

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Make it stick

Identify B and C without colour and qualify the phagocyte example.

If you needed the solution, close it and solve the problem again from a blank page. A correct answer is stronger when you can explain the reason for each step.

Keep learning Sciences — Co-ordinated (9-1)

Course scope and assessment

This 9–1 pathway maps all 152 detailed subject-content sections in the published 0973 syllabus for exams in 2028 and 2029. The course map follows the same 2028–2029 section codes as Cambridge's A*–G 0654 syllabus, while keeping 0973's grading and entry rules separate. It adapts lessons from the related single-science courses and excludes clear single-science-only topics. A 0973-specific objective-by-objective review, Core/Supplement audit, human subject-teacher review, supervised laboratory experience and cumulative assessment remain in progress. Written practice is self-checked and does not predict an official grade. The separate 2025–2027 syllabus has not been reconciled here. Cambridge lists 0973 only in a limited number of administrative zones: June in zone 3 and centres in Oman and the UAE; November in zone 3 only. Confirm entry with your centre.

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