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IGCSE · Cambridge (CIE) · 0973

Interpret independent XX and XY outcomes without a guaranteed family ratio

Equal independent model probabilities give four equally likely ordered outcomes across two conceptions. One of each has probability 50%, but equal small-family counts and alternating outcomes are not guaranteed.

Section B16.1 · Chromosomes and genes

Chromosomes and genes · Cambridge IGCSE 0973 · B16.1
Exam scope and assessment notes

Mapped to the named 0973 section using teaching from the corresponding single-science course. A 0973-specific review of every Core and Supplement objective is still in progress. Written practice is self-checked; it does not demonstrate supervised laboratory competence or award an official Cambridge grade. This qualification reports two grades on the 9–1 scale; confirm the entry route for your zone and exam series.

Before you begin

  • Recall the nucleus, DNA base pairing, gametes, fertilisation, enzymes, membrane carriers and chemical synapses.

Work on paper. Try each question before revealing help, and explain why your method works.

Quick readiness check

After an XX outcome, what is the next XX probability under the stated independent model?

What you will learn

  • Distinguish a model probability from a small-sample outcome
  • Keep independent conceptions and the stated assumptions

Original teaching model. Counts and records are stipulated; drawings are schematic.

Interpret independent XX and XY outcomes without a guaranteed family ratioEqual independent model probabilities give four equally likely ordered outcomes across two conceptions. One of each has probability 50%, but equal small-family counts and alternating outcomes are not guaranteed.Two independent model conceptionsEqual probabilities at each conceptionSecond outcomeXXXYFirst XXFirst XYXX/XXProbability 1/4XX/XYProbability 1/4XY/XXProbability 1/4XY/XYProbability 1/4One of each: 2/4 = 1/2 = 50%No guaranteed family ratio
Equal independent model probabilities give four equally likely ordered outcomes across two conceptions. One of each has probability 50%, but equal small-family counts and alternating outcomes are not guaranteed.
Information, material and count key
FeatureMeaning
Single model outcomeXX 1/2; XY 1/2
Two ordered outcomesFour alternatives, each 1/4
One of eachTwo alternatives = 1/2
LimitNo guaranteed family ratio or compensating outcome

Distinguish a model probability from a small-sample outcome

Assume the stipulated XX/XY model supplies X and Y sperm with equal probabilities and fertilisation does not favour either. With an X egg, the probability of XX is one half and the probability of XY is one half. This describes possible outcomes under the assumptions, not a requirement that a small family must contain equal numbers of each combination.

For two independent conceptions, list ordered combinations: XX then XX, XX then XY, XY then XX, and XY then XY. Under the equal-probability assumptions each ordered outcome has probability one quarter. Two XX outcomes therefore have probability one quarter, while one of each in either order has probability one half because two different ordered outcomes count.

Keep independent conceptions and the stated assumptions

Independence means the previous model outcome does not change the probability for the next conception. A run of XX outcomes does not make a Y sperm contribution due next. The tree diagram is a calculation of specified alternatives; it is not a prediction of an actual family’s future chromosome combinations or a personal reproductive forecast.

An original record of ten XX and six XY outcomes need not contradict a half-and-half probability model, because observed small-sample counts can vary. A larger random sample may approach the expected proportions without guaranteeing them exactly. Biological variation beyond the stipulated model remains outside this calculation, and the model does not establish a person’s identity.

Sources for this lesson

Pause and explain

What is the chance of one XX and one XY in either order for two independent model conceptions?

Put the idea to work

Worked example

Under the model, why is one XX followed by one XY not the only possible two-conception outcome?

Show the worked solution
  1. List all four ordered outcomes.
  2. Recognise each independent conception retains both alternatives.

Answer XX/XX, XX/XY, XY/XX and XY/XY are all possible, so a one-of-each pattern is not guaranteed.

Try a topic test

Choose Easy, Normal or Difficult. Save your answers and open worked review after finishing.

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From guided practice to a new situation

Write your answer and reasoning first. Use a hint only if you are stuck. The model solution is for self-checking; your written work is not automatically marked.

1 · Guided

List all ordered XX/XY outcomes for two independent conceptions.

Give me a hint

Each stage has two alternatives.

Compare my reasoning
  1. Branch first XX into XX and XY.
  2. Branch first XY into XX and XY.

XX/XX, XX/XY, XY/XX and XY/XY are the four ordered outcomes.

Look for these in your work

  • List all four
  • Keep order distinct
2 · Independent

Calculate the chance of two XX outcomes, and of one XX plus one XY in either order.

Give me a hint

Use four equally likely ordered outcomes.

Compare my reasoning
  1. Count one outcome for two XX.
  2. Count two outcomes for one of each.

Two XX: 1/4 or 25%; one of each in either order: 2/4 = 1/2 or 50%.

Look for these in your work

  • Use the right outcome counts
  • Give correct probabilities
3 · Transfer

An original record has ten XX and six XY outcomes. Does a half-probability model require the next outcome to be XY?

Give me a hint

Expected proportion is not a compensating rule.

Compare my reasoning
  1. Recognise sample variation.
  2. Retain independence for the next outcome.

No. Small-sample counts can vary and do not force a compensating outcome; under the stated independent model the next XX and XY probabilities remain one half each.

Look for these in your work

  • Reject forced compensation
  • Retain assumptions and independence

Common mistakes

  • Equal probability does not guarantee equal small-family counts.
  • Previous outcomes do not make the opposite outcome due.
Recall without your notes

What can you explain now?

What is the chance of one XX and one XY in either order for two independent model conceptions?

Compare with the explanation

One half

Two of four equally likely ordered outcomes count.

After trying it yourself, choose your next review. This is your self-assessment.

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Make it stick

Explain distinguish a model probability from a small-sample outcome and keep independent conceptions and the stated assumptions. Use the stated cell, chromosome sets and information pathway before opening the solutions.

If you needed the solution, close it and solve the problem again from a blank page. A correct answer is stronger when you can explain the reason for each step.

Keep learning Sciences — Co-ordinated (9-1)

Course scope and assessment

This 9–1 pathway maps all 152 detailed subject-content sections in the published 0973 syllabus for exams in 2028 and 2029. The course map follows the same 2028–2029 section codes as Cambridge's A*–G 0654 syllabus, while keeping 0973's grading and entry rules separate. It adapts lessons from the related single-science courses and excludes clear single-science-only topics. A 0973-specific objective-by-objective review, Core/Supplement audit, human subject-teacher review, supervised laboratory experience and cumulative assessment remain in progress. Written practice is self-checked and does not predict an official grade. The separate 2025–2027 syllabus has not been reconciled here. Cambridge lists 0973 only in a limited number of administrative zones: June in zone 3 and centres in Oman and the UAE; November in zone 3 only. Confirm entry with your centre.

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