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A Level · Cambridge (CIE) · 9700

Compare prokaryotic and eukaryotic cells

Compare cell organisation, DNA, ribosomes, size and organelles using the evidence supplied for each cell.

Section 1.2 · Cells as the basic units of living organisms

Cells as the basic units pathway · 1.2

AS Level · Cambridge International Biology 9700, 2028–2030. Interpret only the structures supported by the provided image or description. Written practice is self-checked; it does not demonstrate practical microscopy competence.

Before you begin

  • Recognise that organisms are made of cells and that a light microscope produces a magnified image.

Work on paper. Try each question before revealing help, and explain why your method works.

Quick readiness check

Where is a typical bacterium’s circular DNA found?

What you will learn

  • Compare a typical bacterial cell with typical plant and animal cells
  • Use shared and distinguishing features in a structured comparison

Compare the same features in each cell

A typical bacterium is prokaryotic, unicellular and generally 1–5 µm in diameter. It has circular DNA not enclosed in a nucleus, 70S ribosomes, a peptidoglycan cell wall and no double-membraned organelles.

Typical plant and animal cells are eukaryotic and have a nucleus containing linear chromosomes. Their cytoplasm contains 80S ribosomes and membrane-bound organelles such as mitochondria. Typical plant cells also have a cellulose wall, chloroplasts in photosynthetic tissues and a large permanent vacuole.

State similarities as well as differences

All three cell types have a cell-surface membrane, cytoplasm, DNA and ribosomes. Use a named feature for each comparison rather than writing only “more complex”.

A comparison should specify both sides: for example, bacterial DNA is circular and not enclosed in a nucleus, whereas eukaryotic chromosomes are linear and enclosed within a nucleus. If a typical animal cell is compared with a typical plant cell, avoid presenting plant-specific structures as shared by both.

Pause and explain

Which feature is shared by bacterial, plant and animal cells?

Put the idea to work

Worked example

Compare a typical bacterium with a typical animal cell using DNA organisation, ribosomes and membrane-bound organelles.

Show the worked solution
  1. State both structures for each feature.
  2. Include a correct similarity or limitation if useful.

Answer A typical bacterium has circular DNA not enclosed in a nucleus, whereas a typical animal cell has linear chromosomes within a nucleus. Bacteria have 70S ribosomes, whereas eukaryotic cytoplasm has 80S ribosomes. A typical bacterium lacks double-membraned organelles such as mitochondria, while a typical animal cell contains mitochondria.

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From guided practice to a new situation

Write your answer and reasoning first. Use a hint only if you are stuck. The model solution is for self-checking; your written work is not automatically marked.

1 · Guided

Compare a typical bacterium and an animal cell by three features.

Give me a hint

Use the same feature in each side of every comparison.

Compare my reasoning
  1. Bacteria are smaller and lack a nucleus.
  2. They differ in DNA organisation, ribosome type and double-membraned organelles.

A typical bacterium is generally 1–5 µm in diameter and an animal cell is typically larger. Bacterial circular DNA is not enclosed in a nucleus, whereas animal-cell linear chromosomes are nuclear. Bacteria have 70S ribosomes and lack double-membraned organelles; animal-cell cytoplasm has 80S ribosomes and contains mitochondria.

Look for these in your work

  • Three paired comparisons
  • Accurate size or organisation
2 · Independent

State two similarities and two differences between a typical plant cell and a typical bacterium.

Give me a hint

Compare shared boundary/contents and wall or organelles.

Compare my reasoning
  1. Both have a cell-surface membrane and cytoplasm.
  2. Bacteria lack a nucleus and have peptidoglycan; plant cells have a nucleus and cellulose wall.

Both have a cell-surface membrane and cytoplasm. A typical bacterium has circular DNA not enclosed in a nucleus and a peptidoglycan wall; a typical plant cell has a nucleus with linear chromosomes and a cellulose wall, and may contain chloroplasts and a large permanent vacuole.

Look for these in your work

  • Two similarities
  • Two differences correctly paired
3 · Transfer

A comparison table says “both cells have 70S ribosomes.” Identify the error when one cell is a typical eukaryotic animal cell.

Give me a hint

Consider the ribosome location.

Compare my reasoning
  1. Bacterial cytoplasm has 70S ribosomes.
  2. Eukaryotic cytoplasm has 80S; 70S occurs in mitochondria and chloroplasts.

A typical bacterium has 70S ribosomes. A eukaryotic animal-cell cytoplasm has 80S ribosomes. Eukaryotic mitochondria have 70S ribosomes, but that does not make cytoplasmic ribosomes 70S.

Look for these in your work

  • Bacterial type
  • Eukaryotic location distinction

Common mistakes

  • Using “prokaryotes have no DNA”
  • Claiming eukaryotic cells lack 70S ribosomes in organelles
  • Comparing two different features rather than the same feature
Recall without your notes

What can you explain now?

Where is a typical bacterium’s circular DNA found?

Compare with the explanation

Not enclosed in a nucleus

Prokaryotic DNA is not enclosed by a nuclear envelope.

After trying it yourself, choose your next review. This is your self-assessment.

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Make it stick

Which features are shared by all cells, and which distinguish prokaryotes from eukaryotes?

If you needed the solution, close it and solve the problem again from a blank page. A correct answer is stronger when you can explain the reason for each step.

Keep learning Biology

Course scope and assessment

Two hundred and fifty-nine new lessons map every published learning outcome in Cambridge International Biology 9700 Topics 1–19 for exams 2028–2030. Each topic lesson includes guided, independent and transfer practice. Fifteen additional practical-assessment lessons provide online preparation for Paper 3 and Paper 5 practical assessment skills. Online Paper 3 lessons cannot provide supervised laboratory competence. Full timed cumulative exam practice and human subject-teacher review remain outstanding, so this is not exam-readiness evidence.

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