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IGCSE · Cambridge (CIE) · 0973

Describe a hormone and trace its blood-borne route

Connect chemical substance, gland, blood and specific target organs.

Section B13.2 · Hormones

Hormones · Cambridge IGCSE 0973 · B13.2
Exam scope and assessment notes

Mapped to the named 0973 section using teaching from the corresponding single-science course. A 0973-specific review of every Core and Supplement objective is still in progress. Written practice is self-checked; it does not demonstrate supervised laboratory competence or award an official Cambridge grade. This qualification reports two grades on the 9–1 scale; confirm the entry route for your zone and exam series.

Before you begin

  • Recall electrical impulses, blood transport, gland secretion and the distinction between a stimulus and a body response.

Work on paper. Try each question before revealing help, and explain why your method works.

Quick readiness check

What carries a hormone around the body?

What you will learn

  • Follow the source and transport route
  • Explain the specific target response

Describe a hormone and trace its blood-borne route

A gland produces a chemical hormone; blood carries it to specific targets whose activity changes. The route is a teaching model, not a measured delay.Gland produces hormoneBlood carries chemicalSpecific target respondsTransport is not identical response
A gland produces a chemical hormone; blood carries it to specific targets whose activity changes. The route is a teaching model, not a measured delay. Original teaching model.
Hormones model reference
FeatureMeaning
SourceHormone-producing gland
SignalChemical substance
TransportBlood circulation
ResponseAltered activity of one or more specific target organs

Follow the source and transport route

A hormone is a chemical substance made by a gland. The gland releases the hormone into the blood, which carries it through the circulation. At one or more specific target organs, the hormone changes activity. A complete description therefore includes the type of signal, its source, its transport and its effect; simply saying it is a messenger misses important parts.

The producing gland and the responding target are different roles. For example, adrenal glands produce adrenaline, while the heart can respond by beating faster. The chemical substance is the hormone; the heart is not the hormone, and a blood vessel is a transport route rather than automatically a responding target. Name each role before joining the steps into a sentence.

Explain the specific target response

Blood can deliver a hormone to many parts of the body without every organ responding in the same way. Specific target cells can recognise the relevant hormone and change their activity. Receptors provide useful background for this specificity, but the required description here concerns one or more specific target organs rather than detailed receptor chemistry.

Contrast this route with an electrical impulse travelling along a neurone. A hormone is carried as a chemical substance by blood; it does not travel down an axon as an electrical impulse. In a supplied pathway, use the arrows to trace gland production, blood carriage and target action, and avoid swapping the source with the responding organ.

Sources for this lesson

Pause and explain

Which description includes all four required parts?

Put the idea to work

Worked example

Trace adrenaline from production to a heart response.

Show the worked solution
  1. Adrenal glands produce the chemical hormone adrenaline.
  2. Blood carries it to the heart, a target whose activity changes.

Answer Adrenal glands → adrenaline carried by blood → increased heart activity.

Try a topic test

Choose Easy, Normal or Difficult. Save your answers and open worked review after finishing.

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From guided practice to a new situation

Write your answer and reasoning first. Use a hint only if you are stuck. The model solution is for self-checking; your written work is not automatically marked.

1 · Guided

Describe a hormone using its type, source, transport and effect.

Give me a hint

Build the four links in order.

Compare my reasoning
  1. It is a chemical substance produced by a gland.
  2. It is carried by blood and changes activity of specific target organs.

A hormone is a chemical substance produced by a gland, carried by the blood, which alters activity of one or more specific target organs.

Look for these in your work

  • Include chemical and gland
  • Include blood and specific target activity
2 · Independent

In a model, gland X releases chemical Y; blood carries Y to organ Z, whose activity changes. Assign the three roles.

Give me a hint

Separate producer, substance and responder.

Compare my reasoning
  1. X is the producing gland and Y the hormone.
  2. Z is a specific target organ.

X: producing gland; Y: hormone; Z: specific target organ. Blood supplies the transport route.

Look for these in your work

  • Identify all three roles
  • Keep transport distinct
3 · Transfer

Correct: adrenaline is an electrical impulse carried from the heart along an axon.

Give me a hint

Use the source and transport already learned.

Compare my reasoning
  1. Adrenal glands produce adrenaline as a chemical hormone.
  2. Blood carries it to specific targets such as the heart.

Adrenaline is a chemical hormone produced by adrenal glands and carried by blood to specific target organs, including the heart.

Look for these in your work

  • Correct signal and source
  • Correct transport and target

Common mistakes

  • Calling the gland itself a hormone.
  • Replacing blood carriage with an electrical impulse along an axon.
Recall without your notes

What can you explain now?

Which description includes all four required parts?

Compare with the explanation

A gland produces a chemical substance carried by blood to alter specific target organs

It states signal, source, transport and target effect.

After trying it yourself, choose your next review. This is your self-assessment.

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Make it stick

Describe the complete hormone route without confusing gland, hormone, blood and target.

If you needed the solution, close it and solve the problem again from a blank page. A correct answer is stronger when you can explain the reason for each step.

Keep learning Sciences — Co-ordinated (9-1)

Course scope and assessment

This 9–1 pathway maps all 152 detailed subject-content sections in the published 0973 syllabus for exams in 2028 and 2029. The course map follows the same 2028–2029 section codes as Cambridge's A*–G 0654 syllabus, while keeping 0973's grading and entry rules separate. It adapts lessons from the related single-science courses and excludes clear single-science-only topics. A 0973-specific objective-by-objective review, Core/Supplement audit, human subject-teacher review, supervised laboratory experience and cumulative assessment remain in progress. Written practice is self-checked and does not predict an official grade. The separate 2025–2027 syllabus has not been reconciled here. Cambridge lists 0973 only in a limited number of administrative zones: June in zone 3 and centres in Oman and the UAE; November in zone 3 only. Confirm entry with your centre.

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