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IGCSE · Cambridge (CIE) · 0610

Apply aerobic equation amount ratios

Use proportional amounts without inventing a rate.

Section 12.2 · Aerobic respiration

Aerobic respiration pathway · 12.2

Extended only (Supplement); Biology 0610, 2026–2028. Use the stated specimen features and evidence. Diagrams are schematic. Written practice is self-checked

Before you begin

  • Recall cell processes, enzymes and the distinction between gas exchange and breathing.

Work on paper. Try each question before revealing help, and explain why your method works.

Quick readiness check

What does a coefficient show here?

What you will learn

  • Read the reaction ratio
  • Separate amount and elapsed time

Apply aerobic equation amount ratios

Respiration model reference
FeatureMeaning
1 glucoseUses 6 O₂; forms 6 CO₂ + 6 H₂O
2 glucoseUses 12 O₂; forms 12 CO₂ + 12 H₂O
3 glucoseUses 18 O₂; forms 18 CO₂ + 18 H₂O
Rate limitA time measurement is still needed
Original teaching model. These are proportional model counts under the complete glucose reaction. No elapsed time or universal biological rate is implied.

Read the reaction ratio

The balanced equation gives relative molecule amounts: one glucose uses six oxygen and forms six carbon dioxide and six water. Doubling the glucose amount doubles each corresponding amount under the same complete reaction model. This proportional relationship is read from coefficients, not from the sizes of symbols printed on the page.

If twelve oxygen molecules are used in the specified model, two glucose molecules correspond and twelve carbon-dioxide molecules form. These are deliberately small model counts for learning ratios, not measured counts inside a living cell. The same coefficient ratio can apply to proportional chemical amounts, without requiring a molar calculation for this Biology requirement.

Separate amount and elapsed time

An amount is different from a rate. Eighteen carbon-dioxide molecules in the model correspond to three glucose molecules, but no per-second production can be calculated unless a measurement time is supplied. Complete-reaction ratios do not prove all substrate in a live sample was consumed; that depends on the stated conditions and measurements.

In real respiratory measurements, carbon-dioxide production and oxygen use may be influenced by the nutrients being used and other processes. Apply the one-glucose equation when that is the specified model, and avoid treating its ratio as a universal diagnostic of every organism. The task here is a proportional consequence of the balanced syllabus equation.

Pause and explain

How much CO₂ corresponds to three glucose molecules in this complete model?

Put the idea to work

Worked example

Two glucose molecules react completely in the model. Find the oxygen and water amounts.

Show the worked solution
  1. Multiply both coefficient-six quantities by two.
  2. 2 × 6 = 12.

Answer Twelve O₂ molecules used and twelve H₂O molecules formed.

Try a topic test

Choose Easy, Normal or Difficult. Save your answers and open worked review after finishing.

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From guided practice to a new situation

Write your answer and reasoning first. Use a hint only if you are stuck. The model solution is for self-checking; your written work is not automatically marked.

1 · Guided

Four glucose molecules react completely. Find O₂ used and CO₂ formed.

Give me a hint

Use the coefficient-six ratio.

Compare my reasoning
  1. 4 × 6 gives oxygen molecules.
  2. The CO₂ coefficient is also six.

Twenty-four O₂ molecules used and twenty-four CO₂ molecules formed.

Look for these in your work

  • Use proportional coefficients
  • Give both amounts
2 · Independent

Eighteen O₂ molecules are used in this complete glucose model. Find glucose used and water formed.

Give me a hint

Divide oxygen by six, then multiply glucose by six.

Compare my reasoning
  1. 18 ÷ 6 = 3 glucose molecules.
  2. 3 × 6 = 18 water molecules.

Three glucose molecules used; eighteen H₂O molecules formed.

Look for these in your work

  • Reverse the ratio correctly
  • Retain formula identity
3 · Transfer

A model gives twelve CO₂ molecules but no time. Can its CO₂ production rate be calculated?

Give me a hint

Amount per time needs a time.

Compare my reasoning
  1. The equation gives a corresponding amount of two glucose molecules.
  2. A rate requires the elapsed time.

No rate is established without time; the amount ratio corresponds to two glucose molecules in this specified model.

Look for these in your work

  • Distinguish amount and rate
  • Apply the amount ratio

Common mistakes

  • Reading coefficients as seconds.
  • Extending a glucose-specific model to all fuels without evidence.
Recall without your notes

What can you explain now?

How much CO₂ corresponds to three glucose molecules in this complete model?

Compare with the explanation

Eighteen molecules

3 × 6 = 18.

After trying it yourself, choose your next review. This is your self-assessment.

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Make it stick

Use the 1 : 6 : 6 : 6 ratio and keep amount distinct from rate.

If you needed the solution, close it and solve the problem again from a blank page. A correct answer is stronger when you can explain the reason for each step.

Keep learning Biology

Course scope and assessment

780 sequenced lessons provide 2340 guided, independent and application problems in characteristics, classification, cells, organisation, specimen size, membrane transport, biological molecules, enzymes, plant and human nutrition, plant transport, circulatory systems, the heart, blood vessels, blood, disease transmission, body defences, immunity, gas exchange in humans, respiration energy uses and investigations, aerobic respiration, anaerobic respiration and recovery, excretion in humans, coordination and response, sense organs, hormones, homeostasis, tropic responses, drugs, asexual reproduction, sexual reproduction, sexual reproduction in plants, sexual reproduction in humans, sex hormones in humans, sexually transmitted infections, chromosomes, genes and proteins, mitosis, meiosis, monohybrid inheritance, variation, adaptive features, selection, energy flow, food chains and webs, nutrient cycles, population, community, ecosystem, population-growth phases, food supply, habitat destruction, pollution, conservation, biotechnology and genetic modification. 61 of 61 syllabus sections have linked teaching and staged practice. The earlier inheritance overview remains introductory, and the monohybrid pathway develops the relevant Core and Supplement requirements. This is not full programme completion or guaranteed exam readiness. Written practice is self-checked.

StudyForA · Learn with understanding

Original teaching content and links to official sources. Check your exam year and qualification before using a resource.