Learn in your language
Skip to content
IGCSE · Cambridge (CIE) · 0654

Explain why normal mitosis maintains the chromosome number

Normal mitosis maintains the chromosome number in each daughter. Six before copying leads to six in each completed daughter, not six split between them.

Section B16.2 · Cell division

Cell division · Cambridge IGCSE 0654 · B16.2

Mapped to the named 0654 section using teaching from the corresponding single-science course. A 0654-specific review of every Core and Supplement objective is still in progress. Written practice is self-checked; it does not demonstrate supervised laboratory competence or award an official Cambridge grade.

Before you begin

  • Recall chromosomes, genes, chromosome sets, selective gene expression and the distinction between a nucleus and a whole cell.

Work on paper. Try each question before revealing help, and explain why your method works.

Quick readiness check

A six-chromosome parent completes normal mitosis. How many chromosomes are in each daughter?

What you will learn

  • Trace a full complement into each daughter
  • Distinguish maintained number from reduction

Original teaching model. Counts and records are stipulated; drawings are schematic.

Explain why normal mitosis maintains the chromosome numberNormal mitosis maintains the chromosome number in each daughter. Six before copying leads to six in each completed daughter, not six split between them.Supplied chromosome identitiesBefore copying: 6 chromosomesABCDEFExact copying before mitosisABCDEF6 replicated chromosomes; 12 DNA moleculesCopies separateduring mitosisABCDEFABCDEFDaughter 1: 6Daughter 2: 6Every original identity in EACHdaughterBoxes are nuclei; cell division usually follows
Normal mitosis maintains the chromosome number in each daughter. Six before copying leads to six in each completed daughter, not six split between them.
Division, chromosome count and cell-state key
FeatureMeaning
Parent comparisonSix chromosomes before replication
Daughter 1Six chromosomes
Daughter 2Six chromosomes
Both daughters combinedTwelve chromosomes across two cells

Trace a full complement into each daughter

Normal mitosis maintains the chromosome number in each daughter nucleus. The cell first copies its chromosome DNA, then distributes one copy of every chromosome to each product. The copying makes it possible to produce two complete complements rather than splitting a single uncopied list into two incomplete halves. This is the key connection between preparation and the result.

In a stipulated cell with six chromosomes before copying, each daughter cell after normal mitosis and subsequent cell division has six chromosomes. There are twelve chromosomes when the contents of both daughters are added together, but six in each individual daughter. The total across a population and the number per nucleus are different quantities.

Distinguish maintained number from reduction

A division that changes the stated diploid complement to a haploid complement does not fit the chromosome-maintaining mitotic outcome. Meiosis is treated separately in the next syllabus section; this contrast is only a boundary for identifying mitosis, not a replacement for the full meiosis sequence. Gamete formation and fertilisation must not be inserted into the ordinary mitotic copying model.

Count the supplied model at comparable points: the parent before replication and the completed daughter nuclei after separation. During preparation, each replicated chromosome has two attached DNA copies, which can create a counting trap. The later lessons explicitly distinguish chromosome number from DNA-copy number so the maintained-number explanation does not silently change its counting rule.

Sources for this lesson

Pause and explain

Which comparison correctly tests maintained number?

Put the idea to work

Worked example

A parent has six chromosomes. What number is expected in each normal mitotic daughter?

Show the worked solution
  1. Use maintained number per daughter.
  2. Separate that from the sum across both products.

Answer Each daughter has six; both daughters together contain twelve.

Try a topic test

Choose Easy, Normal or Difficult. Save your answers and open worked review after finishing.

Test this topic →

From guided practice to a new situation

Write your answer and reasoning first. Use a hint only if you are stuck. The model solution is for self-checking; your written work is not automatically marked.

1 · Guided

State how copying and separation maintain a six-chromosome complement.

Give me a hint

Give each daughter every represented chromosome.

Compare my reasoning
  1. Copy each chromosome before mitosis.
  2. Separate the copies into two full complements.

Each chromosome is copied before mitosis, then one copy of each is distributed to each daughter nucleus, giving six in each.

Look for these in your work

  • Include copying before division
  • Explain complete distribution
2 · Independent

Two completed daughters each contain eight chromosomes. State the per-cell number and their combined total.

Give me a hint

Do not confuse one cell with both.

Compare my reasoning
  1. Read eight in each cell.
  2. Add eight plus eight.

The per-cell number is eight; the combined total across the two cells is sixteen.

Look for these in your work

  • State the per-cell value
  • Label the combined total
3 · Transfer

A record stipulates that a diploid six-chromosome parent gives haploid three-chromosome products. Does it describe normal mitosis?

Give me a hint

Compare the number and chromosome sets.

Compare my reasoning
  1. Identify the reduction from six to three.
  2. Compare with the maintained-number definition.

No. The stated reduction from diploid to haploid is inconsistent with normal chromosome-maintaining mitosis; full meiosis teaching remains a separate section.

Look for these in your work

  • Identify the reduction
  • Keep the wider section boundary

Common mistakes

  • Use per-cell counts when explaining maintained chromosome number.
  • Mitosis is not the diploid-to-haploid reduction division.
Recall without your notes

What can you explain now?

Which comparison correctly tests maintained number?

Compare with the explanation

Parent before replication versus each completed daughter nucleus

Use comparable complete complements.

After trying it yourself, choose your next review. This is your self-assessment.

Your review choice appears on Today. Sign in to sync it across devices.

Make it stick

Without your notes, trace a full complement into each daughter and distinguish maintained number from reduction. Distinguish nuclear division, chromosome copies and completed daughter cells before opening the solutions.

If you needed the solution, close it and solve the problem again from a blank page. A correct answer is stronger when you can explain the reason for each step.

Keep learning Sciences — Co-ordinated (Double)

Course scope and assessment

This 2028–2029 pathway maps all 152 detailed subject-content sections in the published 0654 syllabus to original teaching and staged practice. It adapts teaching from the related single-science pathways and excludes clear 0610-only topics such as classification systems, human excretion, tropic responses, food supply, population dynamics, detailed pollution and biotechnology. Some explanations may include wider single-science context. A 0654-specific objective-by-objective review, Core/Supplement audit, human subject-teacher review, supervised laboratory experience and cumulative assessment remain in progress. Written practice is self-checked and does not predict an official grade. The 2025–2027 syllabus has not been reconciled here; choose the 2028–2029 syllabus only.

StudyForA · Learn with understanding

Original teaching content and links to official sources. Check your exam year and qualification before using a resource.