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A Level · Cambridge (CIE) · 9700

Distinguish haploid and diploid nuclei

Explain chromosome-set number using n and 2n and connect it to gametes and fertilisation.

Passage of information from parents to offspring pathway · 16.1

A Level; Cambridge International Biology 9700, 2028–2030. Written answers are self-checked; this is not practical-skills certification.

Before you begin

  • Genes are DNA sequences that can be inherited; meiosis and fertilisation link parental genomes.

Work on paper. Try each question before revealing help, and explain why your method works.

Quick readiness check

What does n represent in a haploid nucleus?

What you will learn

  • Define haploid (n) as one complete chromosome set
  • Define diploid (2n) as two chromosome sets

Original teaching model. Counts, source combinations and sample records are stipulated; drawings are schematic.

Explain reduction from diploid to haploid chromosome setsReduction halves the complement per nucleus: two complete sets become one.Stipulated n = 3 count modelDiploid precursor: 2n = 61A1B2A2B3A3BFinal meiotic products: onecomplete set EACH123Product 1: 3123Product 2: 3123Product 3: 3123Product 4: 3Four boundaries; 3 chromosomes in eachType labels do not show all allelecombinations
Reduction halves the complement per nucleus: two complete sets become one.
Chromosome sets, combinations and evidence key
FeatureMeaning
Referencen = 3 means one complete set of three types
Diploid precursor2n = 6 chromosomes in one nucleus
Normal haploid productn = 3 chromosomes in each product nucleus
Across separate productsA combined total is not the complement of one nucleus

Build the genetic explanation

A haploid nucleus has one complete set of chromosomes, written n. A diploid nucleus has two sets, written 2n, typically one homologous set from each parent. Gametes are haploid; fertilisation fuses nuclei and restores the diploid number in a zygote. The value of n is a number of chromosome types, not the total number of DNA molecules in every cell state.

Check the evidence and limits

A replicated chromosome still counts as one chromosome until sister chromatids separate at the centromere. Do not confuse DNA molecule number with chromosome-set number.

Pause and explain

A fertilised egg receives one haploid set from each parent. State its ploidy and why.

Put the idea to work

Worked example

A species has n=4. How many chromosomes are in a diploid nucleus?

Show the worked solution
  1. Diploid means two complete sets.
  2. Calculate 2n=2×4.

Answer 2n=8 chromosomes.

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From guided practice to a new situation

Write your answer and reasoning first. Use a hint only if you are stuck. The model solution is for self-checking; your written work is not automatically marked.

1 · Guided

A species has n=7. State the diploid chromosome number and explain the calculation.

Give me a hint

Set out the alleles or steps before deciding the outcome.

Compare my reasoning
  1. Diploid has two chromosome sets.
  2. Multiply n by two.

The diploid number is 2n=14 because a diploid nucleus contains two complete sets of seven chromosomes.

Look for these in your work

  • Genetic terms used correctly
  • Steps linked
2 · Independent

A haploid gamete contains one chromosome of each type. Is it necessarily a cell with half the DNA molecules of every diploid cell? Explain.

Give me a hint

Use the given evidence and state your assumptions.

Compare my reasoning
  1. Haploid and diploid refer to chromosome sets.
  2. DNA replication and cell-cycle stage affect DNA-molecule number.

No. Haploid describes one chromosome set, while DNA-molecule number depends on replication and cell state. A replicated chromosome still belongs to one set until its chromatids separate.

Look for these in your work

  • Prediction or interpretation supported
  • Limits stated
3 · Transfer

A fertilised egg receives one haploid set from each parent. State its ploidy and why.

Give me a hint

Apply the inheritance or gene-control model to the new context.

Compare my reasoning
  1. The two haploid nuclei fuse.
  2. One set plus one set makes two sets.

The zygote is diploid (2n), because fertilisation combines one haploid set from each parent.

Look for these in your work

  • Model applied accurately
  • Unsupported certainty avoided

Common mistakes

  • Treating n as a count of chromatids
  • Calling a diploid nucleus four sets because each chromosome has replicated
Recall without your notes

What can you explain now?

What does n represent in a haploid nucleus?

Compare with the explanation

One complete set of chromosomes

It is one representative of each chromosome type.

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Make it stick

What do n and 2n count?

If you needed the solution, close it and solve the problem again from a blank page. A correct answer is stronger when you can explain the reason for each step.

Keep learning Biology

Course scope and assessment

Two hundred and fifty-nine new lessons map every published learning outcome in Cambridge International Biology 9700 Topics 1–19 for exams 2028–2030. Each topic lesson includes guided, independent and transfer practice. Fifteen additional practical-assessment lessons provide online preparation for Paper 3 and Paper 5 practical assessment skills. Online Paper 3 lessons cannot provide supervised laboratory competence. Full timed cumulative exam practice and human subject-teacher review remain outstanding, so this is not exam-readiness evidence.

StudyForA · Learn with understanding

Original teaching content and links to official sources. Check your exam year and qualification before using a resource.