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A Level · Cambridge (CIE) · 9700

Explain the cardiac cycle

Relate pressure changes during systole and diastole to atrioventricular and semilunar valve movement.

The mammalian heart pathway · 8.3

AS Level; Cambridge International Biology 9700, 2028–2030. Written practice is self-checked; microscope recognition, biological drawing and supervised practical competence require practical work, while human subject-teacher review remains pending.

Before you begin

  • Know that mass transport moves substances between exchange surfaces and cells, and that diffusion occurs down a concentration or partial-pressure gradient.

Work on paper. Try each question before revealing help, and explain why your method works.

Quick readiness check

What causes the atrioventricular valves to close during ventricular systole?

What you will learn

  • Describe atrial and ventricular systole and diastole
  • Explain valve opening and closure using pressure differences
Normal simplified sequence: filling has atrioventricular valves open; ejection has semilunar valves open; pressure differences drive the transitions and prevent backflow.One repeating cardiac cycleFillingAtrioventricular open; exitsshutEjectionAtrioventricular shut; exitsopenRelaxationExit valves shut; fillingresumes
Normal simplified sequence: filling has atrioventricular valves open; ejection has semilunar valves open; pressure differences drive the transitions and prevent backflow.

Build the explanation

During atrial systole, atrial contraction raises atrial pressure above ventricular pressure; atrioventricular valves are open and blood enters ventricles. During ventricular systole, ventricular pressure rises above atrial pressure and closes the atrioventricular valves. When ventricular pressure exceeds pressure in the aorta and pulmonary artery, semilunar valves open and blood is ejected. During ventricular diastole, ventricular pressure falls; semilunar valves close as arterial pressure exceeds ventricular pressure. When ventricular pressure falls below atrial pressure, atrioventricular valves open and filling resumes.

Apply it carefully

Valves move passively in response to pressure differences; they do not open because an electrical signal pulls them. 'Systole' means contraction and 'diastole' means relaxation. State which chamber pressure is higher than which neighbouring pressure at each valve event. The cycle is continuous; simplified diagrams often separate phases for learning.

Pause and explain

When do semilunar valves open?

Put the idea to work

Worked example

Why does the left atrioventricular valve close at the start of ventricular systole?

Show the worked solution
  1. Ventricular contraction raises pressure.
  2. Ventricular pressure becomes greater than atrial pressure.

Answer The left ventricular pressure rises above left atrial pressure, forcing the atrioventricular valve closed and preventing backflow into the atrium.

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From guided practice to a new situation

Write your answer and reasoning first. Use a hint only if you are stuck. The model solution is for self-checking; your written work is not automatically marked.

1 · Guided

Explain the sequence that opens the aortic semilunar valve.

Give me a hint

Compare ventricular and aortic pressure.

Compare my reasoning
  1. Ventricular systole raises left ventricular pressure.
  2. When it exceeds aortic pressure, the aortic valve opens and blood is ejected.

During left ventricular systole, ventricular pressure rises. When it becomes greater than aortic pressure, the semilunar valve opens and blood is ejected into the aorta.

Look for these in your work

  • Systole raises pressure
  • Pressure comparison correct
  • Opening and ejection linked
2 · Independent

During ventricular diastole, aortic pressure is greater than left ventricular pressure. Predict the semilunar valve state and explain why.

Give me a hint

A higher pressure on the artery side pushes the valve closed.

Compare my reasoning
  1. The aortic semilunar valve closes.
  2. This prevents blood flowing backwards into the ventricle.

The aortic semilunar valve closes because aortic pressure exceeds ventricular pressure, preventing backflow from the artery into the ventricle.

Look for these in your work

  • Valve state correct
  • Pressure cause stated
  • Backflow prevented
3 · Transfer

Put these events in order: AV valves open; ventricular pressure rises; AV valves close; semilunar valves open.

Give me a hint

Start with filling, then pressure reversal at the start of ventricular contraction.

Compare my reasoning
  1. AV valves open during filling.
  2. Ventricular pressure rises, closes AV valves, then exceeds arterial pressure so semilunar valves open.

AV valves open during ventricular filling → ventricular pressure rises during systole → AV valves close when ventricular pressure exceeds atrial pressure → semilunar valves open when ventricular pressure exceeds arterial pressure.

Look for these in your work

  • All events ordered
  • Both pressure thresholds stated

Common mistakes

  • Saying valves open due to contraction rather than a pressure difference
  • Swapping systole and diastole
  • Omitting the arterial pressure threshold for semilunar opening
Recall without your notes

What can you explain now?

What causes the atrioventricular valves to close during ventricular systole?

Compare with the explanation

Ventricular pressure exceeds atrial pressure

The pressure reversal pushes the valves closed.

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Make it stick

What pressure relationships close AV valves, open semilunar valves and then close semilunar valves?

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Keep learning Biology

Course scope and assessment

Two hundred and fifty-nine new lessons map every published learning outcome in Cambridge International Biology 9700 Topics 1–19 for exams 2028–2030. Each topic lesson includes guided, independent and transfer practice. Fifteen additional practical-assessment lessons provide online preparation for Paper 3 and Paper 5 practical assessment skills. Online Paper 3 lessons cannot provide supervised laboratory competence. Full timed cumulative exam practice and human subject-teacher review remain outstanding, so this is not exam-readiness evidence.

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