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IGCSE · Cambridge (CIE) · 0973

Describe a drug by its effect on body chemistry

Use a biological definition that is broader than illegal substances.

Drugs · Cambridge IGCSE 0973 · B14.1
Exam scope and assessment notes

Mapped to the named 0973 section using teaching from the corresponding single-science course. A 0973-specific review of every Core and Supplement objective is still in progress. Written practice is self-checked; it does not demonstrate supervised laboratory competence or award an official Cambridge grade. This qualification reports two grades on the 9–1 scale; confirm the entry route for your zone and exam series.

Before you begin

  • Distinguish bacteria from viruses; recall enzymes, chemical reactions, pathogens and reproduction of bacteria.

Work on paper. Try each question before revealing help, and explain why your method works.

Quick readiness check

Which pair belongs in the biological definition?

What you will learn

  • Include entry into the body and a chemical effect
  • Distinguish a drug from a device or an internal signal

Describe a drug by its effect on body chemistry

Biological definition: an introduced substance affects chemical reactions inside the body. Legal medicines can fit; a measuring device is a different category.Substance introduced into bodyAffects chemical reactions thereFits this biological drug definition
Biological definition: an introduced substance affects chemical reactions inside the body. Legal medicines can fit; a measuring device is a different category. Original teaching model.
Drug and antibiotic model reference
FeatureMeaning
EntrySubstance introduced into the body
EffectChanges or influences chemical reactions
ScopeCan include medicines; not limited to illegal substances
ContextInternal hormone production differs from an introduced preparation

Include entry into the body and a chemical effect

In this biology section, a drug is a substance introduced into the body that changes or influences chemical reactions within it. The definition includes two links: the substance is taken into the body, and it affects body chemistry. The word drug does not mean only an illegal substance, and a substance need not cause addiction to fit this biological account.

Medicines can be drugs because their chemical effects are used in treatment. For example, a supplied model substance may inhibit a reaction involved in producing a pain signal. A medical device such as an external thermometer measures a condition; the device itself is not a substance introduced to alter body reactions. Classify the role described in the question rather than judging an object only by where it is found.

Distinguish a drug from a device or an internal signal

A drug can increase, decrease or otherwise alter a particular chemical process. It does not have to stop every reaction in the body. Insulin made naturally by the pancreas is an internal hormone signal; a supplied insulin preparation introduced for treatment can also act as a drug. The same named chemical can have different source contexts, so distinguish normal production inside the body from a substance given from outside.

A definition identifies a category, not whether taking a particular substance is safe or medically appropriate. These lessons use invented reaction and pathogen models to practise biological reasoning; they do not ask learners to choose a medicine or a dose. Include the body-entry and chemical-effect links when defining a drug, then use the specific evidence supplied for its effect.

Sources for this lesson

Pause and explain

Can a prescribed medicine fit the definition of a drug?

Put the idea to work

Worked example

A supplied substance enters the body and slows reaction X. Why does it fit the biological definition?

Show the worked solution
  1. The substance is introduced into the body.
  2. It changes a chemical reaction there.

Answer It is a drug in this biological model because it enters the body and affects a chemical reaction.

Try a topic test

Choose Easy, Normal or Difficult. Save your answers and open worked review after finishing.

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From guided practice to a new situation

Write your answer and reasoning first. Use a hint only if you are stuck. The model solution is for self-checking; your written work is not automatically marked.

1 · Guided

Define a drug in biological terms.

Give me a hint

Include both the introduced substance and its chemical effect.

Compare my reasoning
  1. It is a substance taken into the body.
  2. It changes or influences chemical reactions within the body.

A drug is a substance introduced into the body that changes or influences chemical reactions within it.

Look for these in your work

  • Include entry into the body
  • Include an effect on chemical reactions
2 · Independent

Why is an external thermometer not itself a drug in this definition?

Give me a hint

Its role is measurement rather than an introduced chemical effect.

Compare my reasoning
  1. It is a measuring device.
  2. The device is not a substance introduced to alter body reactions.

An external thermometer is a measuring device, not a substance introduced into the body to affect chemical reactions.

Look for these in your work

  • Identify the device role
  • Apply both definition links
3 · Transfer

Distinguish insulin produced naturally in the pancreas from an insulin preparation introduced in a supplied treatment model.

Give me a hint

The chemical name is the same but the source context differs.

Compare my reasoning
  1. Natural production supplies an internal hormone signal.
  2. The introduced preparation can act as a drug affecting body chemistry.

Naturally produced insulin is an internal hormone signal; an introduced insulin preparation can also act as a drug because it is given from outside and affects body chemistry.

Look for these in your work

  • Distinguish the two sources
  • Explain the introduced substance role

Common mistakes

  • Defining drugs only as illegal substances.
  • Saying every drug stops all body chemistry.
Recall without your notes

What can you explain now?

Can a prescribed medicine fit the definition of a drug?

Compare with the explanation

Yes, if introduced into the body to affect chemical reactions

Legal medicines can fit the biological definition.

After trying it yourself, choose your next review. This is your self-assessment.

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Make it stick

Define a drug using both required links and distinguish a chemical treatment from a measuring device.

If you needed the solution, close it and solve the problem again from a blank page. A correct answer is stronger when you can explain the reason for each step.

Keep learning Sciences — Co-ordinated (9-1)

Course scope and assessment

This 9–1 pathway maps all 152 detailed subject-content sections in the published 0973 syllabus for exams in 2028 and 2029. The course map follows the same 2028–2029 section codes as Cambridge's A*–G 0654 syllabus, while keeping 0973's grading and entry rules separate. It adapts lessons from the related single-science courses and excludes clear single-science-only topics. A 0973-specific objective-by-objective review, Core/Supplement audit, human subject-teacher review, supervised laboratory experience and cumulative assessment remain in progress. Written practice is self-checked and does not predict an official grade. The separate 2025–2027 syllabus has not been reconciled here. Cambridge lists 0973 only in a limited number of administrative zones: June in zone 3 and centres in Oman and the UAE; November in zone 3 only. Confirm entry with your centre.

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