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IGCSE · Cambridge (CIE) · 0973

Identify red and white blood cells in diagrams

Use nucleus, cell outline and central pallor in a schematic comparison.

Blood · Cambridge IGCSE 0973 · B9.4
Exam scope and assessment notes

Mapped to the named 0973 section using teaching from the corresponding single-science course. A 0973-specific review of every Core and Supplement objective is still in progress. Written practice is self-checked; it does not demonstrate supervised laboratory competence or award an official Cambridge grade. This qualification reports two grades on the 9–1 scale; confirm the entry route for your zone and exam series.

Before you begin

  • Recall the four blood components.

Work on paper. Try each question before revealing help, and explain why your method works.

Quick readiness check

What is a nucleus?

What you will learn

  • Recognise the mature red-cell pattern
  • White cells retain a nucleus
A mature human red cell; B and C white cells. Central pallor in A is not a nucleus or an open hole. Relative drawn sizes are schematic.Red cells and nucleatedwhite cellsA: mature red cellCentral pallor; no nucleusB: lymphocyteLarge round nucleusC: phagocyte (neutrophil)Lobed nucleus; cytoplasm
A mature human red cell; B and C white cells. Central pallor in A is not a nucleus or an open hole. Relative drawn sizes are schematic. Original schematic, not to scale.

Recognise the mature red-cell pattern

The original diagram labels A as a mature human red blood cell. It is drawn as a biconcave disc viewed from above: the centre is paler than the rim, and there is no nucleus. The pale centre represents the thinner central region, not an open hole through the cell.

Mature human red cells lack a nucleus, but not all animals have that pattern and developing cells differ. Use the stated human specimen. A drawing is simplified and not to scale; its size on the screen does not provide an actual diameter.

White cells retain a nucleus

B and C are white blood cells. B has a large round nucleus; C has a lobed nucleus with surrounding cytoplasm. Their shared nucleated pattern distinguishes them from mature human red cells. White cells have different shapes and functions, so do not insist that every white-cell nucleus looks the same.

Colour is a teaching convention in this diagram. Identify A using its disc-like outline and lack of nucleus, and B/C using their nuclei. The detailed lymphocyte/phagocyte names are explored in the Extended sequence. Core identification here asks for red or white cells using observable features rather than disease diagnosis.

Sources for this lesson

Pause and explain

Which diagram feature supports white-cell identification?

Put the idea to work

Worked example

Identify A and B/C as red or white cells and give evidence independent of colour.

Show the worked solution
  1. A has no nucleus and a paler disc centre.
  2. B and C contain nuclei.

Answer A mature human red cell; B and C white cells. The presence or absence of a nucleus supports the distinction.

Try a topic test

Choose Easy, Normal or Difficult. Save your answers and open worked review after finishing.

Test this topic →

From guided practice to a new situation

Write your answer and reasoning first. Use a hint only if you are stuck. The model solution is for self-checking; your written work is not automatically marked.

1 · Guided

Identify A and state two visible features supporting the answer.

Give me a hint

Use shape and nucleus evidence.

Compare my reasoning
  1. A is disc-like with a paler central region.
  2. It has no nucleus.

A mature human red blood cell: disc-like central pallor and no nucleus.

Look for these in your work

  • Name the cell
  • Use two structural features
2 · Independent

Identify B and C at the Core red/white-cell level.

Give me a hint

Their nucleus shapes differ but both have one.

Compare my reasoning
  1. B has a round nucleus.
  2. C has a lobed nucleus.

B and C are white blood cells; both contain a nucleus.

Look for these in your work

  • Identify both
  • Use nucleus evidence
3 · Transfer

The diagram is printed in grayscale. How can A still be distinguished from B and C?

Give me a hint

Focus on structures rather than colour.

Compare my reasoning
  1. A lacks a nucleus and has a pale disc centre.
  2. B/C show nuclei and surrounding cytoplasm.

Use A’s lack of nucleus and disc structure versus the nuclei in B/C; colour is unnecessary.

Look for these in your work

  • Compare structures
  • Retain evidence without colour

Common mistakes

  • Calling central pallor a nucleus.
  • Treating all white-cell nuclei as identical.
Recall without your notes

What can you explain now?

Which diagram feature supports white-cell identification?

Compare with the explanation

A nucleus within the cell

B and C have nuclei.

After trying it yourself, choose your next review. This is your self-assessment.

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Make it stick

Identify the red and white cells with their colours covered.

If you needed the solution, close it and solve the problem again from a blank page. A correct answer is stronger when you can explain the reason for each step.

Keep learning Sciences — Co-ordinated (9-1)

Course scope and assessment

This 9–1 pathway maps all 152 detailed subject-content sections in the published 0973 syllabus for exams in 2028 and 2029. The course map follows the same 2028–2029 section codes as Cambridge's A*–G 0654 syllabus, while keeping 0973's grading and entry rules separate. It adapts lessons from the related single-science courses and excludes clear single-science-only topics. A 0973-specific objective-by-objective review, Core/Supplement audit, human subject-teacher review, supervised laboratory experience and cumulative assessment remain in progress. Written practice is self-checked and does not predict an official grade. The separate 2025–2027 syllabus has not been reconciled here. Cambridge lists 0973 only in a limited number of administrative zones: June in zone 3 and centres in Oman and the UAE; November in zone 3 only. Confirm entry with your centre.

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