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IGCSE · Cambridge (CIE) · 0973

Describe a synapse as a junction between neurones

Separate the whole junction from the small gap within it.

Coordination and response · Cambridge IGCSE 0973 · B13.1
Exam scope and assessment notes

Mapped to the named 0973 section using teaching from the corresponding single-science course. A 0973-specific review of every Core and Supplement objective is still in progress. Written practice is self-checked; it does not demonstrate supervised laboratory competence or award an official Cambridge grade. This qualification reports two grades on the 9–1 scale; confirm the entry route for your zone and exam series.

Before you begin

  • Recall cell membranes, diffusion, sensitivity and the difference between cells, tissues and organs.

Work on paper. Try each question before revealing help, and explain why your method works.

Quick readiness check

How many separate neurones are named in the required synapse definition?

What you will learn

  • Neurones meet at specialised junctions
  • The gap is one part of the synapse

Describe a synapse as a junction between neurones

A synapse is a junction between two neurones. In the chemical model the gap is one part of the whole specialised junction, not its entire definition. Original teaching model.

Neural model reference
FeatureMeaning
Participating cellsTwo separate neurones
ConnectionSynaptic junction
GapSpace between cell regions in the chemical model
InterpretationA connecting line does not mean cell fusion

Neurones meet at specialised junctions

A synapse is a junction between two neurones in the required Core account. It connects communication from one nerve cell with the next in a pathway. The neurones remain separate cells rather than becoming one continuous cell simply because information can pass between them.

In the chemical-synapse model developed in Supplement teaching, the terminal of the first neurone is separated from the next cell by a synaptic gap. The entire junction includes the adjoining specialised cell regions as well as that gap. Synapse should therefore not be defined only as an empty space with no participating cells.

The gap is one part of the synapse

A simple reflex arc includes junctions between its sensory, relay and motor communicating cells. These links allow input to be integrated with output in the supplied pathway. A motor connection to a muscle is a related specialised junction, but this numbered Core requirement specifically asks for a junction between two neurones.

Electrical impulses travel along neurones, while a chemical junction uses neurotransmitter release, diffusion and binding in the Extended account. The Core definition does not require every intermediate mechanism, but it should preserve the two-cell junction idea. A drawn line linking two neurones summarises communication rather than proving their cell membranes are fused into one uninterrupted tube.

Sources for this lesson

Pause and explain

Which is the required definition?

Put the idea to work

Worked example

Define a synapse in the required Core account.

Show the worked solution
  1. Name the junction.
  2. Specify the two participating nerve cells.

Answer A synapse is a junction between two neurones.

Try a topic test

Choose Easy, Normal or Difficult. Save your answers and open worked review after finishing.

Test this topic →

From guided practice to a new situation

Write your answer and reasoning first. Use a hint only if you are stuck. The model solution is for self-checking; your written work is not automatically marked.

1 · Guided

State the required Core definition of a synapse.

Give me a hint

Use junction and two neurones.

Compare my reasoning
  1. It is a communication junction.
  2. The participating cells are two neurones.

A synapse is a junction between two neurones.

Look for these in your work

  • Name a junction
  • Name two neurones
2 · Independent

Distinguish the synaptic gap from the whole chemical synapse.

Give me a hint

The junction also includes specialised parts of the two cells.

Compare my reasoning
  1. The gap is the space between them.
  2. The synapse includes the whole specialised junction.

The synaptic gap is one part of the chemical synapse; the whole junction also involves specialised regions of the two separate neurones.

Look for these in your work

  • Separate gap and junction
  • Retain the two cells
3 · Transfer

A drawing links two neurones with a line. Does this establish that they have fused into one cell?

Give me a hint

A connection can summarise transmission without fusion.

Compare my reasoning
  1. The neurones remain separate.
  2. A synapse links their communication.

No. The line summarises a synaptic connection between separate neurones; it does not establish cell fusion.

Look for these in your work

  • Recognise schematic meaning
  • Keep the two cells separate

Common mistakes

  • Defining the whole synapse only as empty space.
  • Saying the two neurones fuse into one cell.
Recall without your notes

What can you explain now?

Which is the required definition?

Compare with the explanation

Junction between two neurones

It preserves the cell-to-cell connection.

After trying it yourself, choose your next review. This is your self-assessment.

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Make it stick

Define a synapse and distinguish the gap from the complete junction.

If you needed the solution, close it and solve the problem again from a blank page. A correct answer is stronger when you can explain the reason for each step.

Keep learning Sciences — Co-ordinated (9-1)

Course scope and assessment

This 9–1 pathway maps all 152 detailed subject-content sections in the published 0973 syllabus for exams in 2028 and 2029. The course map follows the same 2028–2029 section codes as Cambridge's A*–G 0654 syllabus, while keeping 0973's grading and entry rules separate. It adapts lessons from the related single-science courses and excludes clear single-science-only topics. A 0973-specific objective-by-objective review, Core/Supplement audit, human subject-teacher review, supervised laboratory experience and cumulative assessment remain in progress. Written practice is self-checked and does not predict an official grade. The separate 2025–2027 syllabus has not been reconciled here. Cambridge lists 0973 only in a limited number of administrative zones: June in zone 3 and centres in Oman and the UAE; November in zone 3 only. Confirm entry with your centre.

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