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IGCSE · Cambridge (CIE) · 0654

Distinguish chromosome-set number from total chromosome count

Use total and supplied n together: 12/n gives two sets when n = 6 and one set when n = 12. An unlabelled total alone does not determine ploidy across different models.

Chromosomes and genes · Cambridge IGCSE 0654 · B16.1

Mapped to the named 0654 section using teaching from the corresponding single-science course. A 0654-specific review of every Core and Supplement objective is still in progress. Written practice is self-checked; it does not demonstrate supervised laboratory competence or award an official Cambridge grade.

Before you begin

  • Recall the nucleus, DNA base pairing, gametes, fertilisation, enzymes, membrane carriers and chemical synapses.

Work on paper. Try each question before revealing help, and explain why your method works.

Quick readiness check

Which information helps interpret a chromosome total as sets?

What you will learn

  • Use a supplied set size to interpret totals
  • Recognise when an unlabelled total is insufficient

Original teaching model. Counts and records are stipulated; drawings are schematic.

Distinguish chromosome-set number from total chromosome countUse total and supplied n together: 12/n gives two sets when n = 6 and one set when n = 12. An unlabelled total alone does not determine ploidy across different models.Set sizen: chromosomes in one setTotalNumber of individual chromosomesModel ATotal 12; n 6 → two setsModel BTotal 12; n 12 → one set
Use total and supplied n together: 12/n gives two sets when n = 6 and one set when n = 12. An unlabelled total alone does not determine ploidy across different models.
Information, material and count key
FeatureMeaning
Set sizen: chromosomes in one set
TotalNumber of individual chromosomes
Model ATotal 12; n 6 → two sets
Model BTotal 12; n 12 → one set

Use a supplied set size to interpret totals

Chromosome-set number and total chromosome count are different quantities. If a model’s single set contains three chromosomes, one set has 3 and two sets have 6. The relationship uses the specified set size; a total without information about the organism or its chromosome types may be insufficient to determine how many sets it represents.

Consider two stipulated models both with a total of 12 chromosomes. Model A has n = 6, so its total represents two sets. Model B has n = 12, so its total represents one set. Equal totals therefore do not establish equal ploidy across models with different set sizes. The numbers are invented teaching cases, not counts assigned to a named natural species.

Recognise when an unlabelled total is insufficient

A labelled chromosome drawing can provide the missing type information. One representative of each supplied type represents one set; two representatives across the corresponding types represent two sets in this simple model. An unlabelled rod collection does not reveal that relationship merely through its overall size or colour.

The original comparison table asks for both n and set number before giving a total. Keep the categories explicit in calculations: chromosome individuals are counted as objects, while sets are groups containing the supplied types. These models use unreplicated chromosomes and do not ask learners to infer a DNA-copy stage or count sister chromatids.

Sources for this lesson

Pause and explain

A model has n = 6 and total 12. How many sets does that represent?

Put the idea to work

Worked example

Why can a total of 12 chromosomes represent different set numbers in two models?

Show the worked solution
  1. Identify the different supplied n values.
  2. Divide the total by each stated set size.

Answer With n = 6, 12 represents two sets; with n = 12, it represents one set. The total alone does not fix ploidy across different models.

Try a topic test

Choose Easy, Normal or Difficult. Save your answers and open worked review after finishing.

Test this topic →

From guided practice to a new situation

Write your answer and reasoning first. Use a hint only if you are stuck. The model solution is for self-checking; your written work is not automatically marked.

1 · Guided

Calculate totals for one and two sets in an n = 3 model.

Give me a hint

Multiply the given size by the number of sets.

Compare my reasoning
  1. Use one times three.
  2. Use two times three.

One set has 3 chromosomes; two sets have 6 chromosomes in the stipulated model.

Look for these in your work

  • Give both totals
  • Distinguish set number
2 · Independent

Compare total 12 with n = 6 and total 12 with n = 12.

Give me a hint

Use the total-to-set-size ratio separately.

Compare my reasoning
  1. Calculate 12/6.
  2. Calculate 12/12.

The n = 6 model has two sets; the n = 12 model has one set despite the equal total.

Look for these in your work

  • Use both supplied n values
  • Explain equal-total limitation
3 · Transfer

An unlabelled drawing has twelve rods but gives no species or type key. Can it establish haploid or diploid?

Give me a hint

The one-set size is missing.

Compare my reasoning
  1. Identify the total shown.
  2. State that n or corresponding-type evidence is absent.

No. The total is twelve, but without n or chromosome-type information it does not establish whether the drawing represents one set or two.

Look for these in your work

  • Keep the visible count
  • State missing set evidence

Common mistakes

  • An unlabelled total does not give every model’s ploidy.
  • Do not count sets and individuals as the same quantity.
Recall without your notes

What can you explain now?

A model has n = 6 and total 12. How many sets does that represent?

Compare with the explanation

Two sets

12 divided by 6 is 2.

After trying it yourself, choose your next review. This is your self-assessment.

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Make it stick

Explain use a supplied set size to interpret totals and recognise when an unlabelled total is insufficient. Use the stated cell, chromosome sets and information pathway before opening the solutions.

If you needed the solution, close it and solve the problem again from a blank page. A correct answer is stronger when you can explain the reason for each step.

Keep learning Sciences — Co-ordinated (Double)

Course scope and assessment

This 2028–2029 pathway maps all 152 detailed subject-content sections in the published 0654 syllabus to original teaching and staged practice. It adapts teaching from the related single-science pathways and excludes clear 0610-only topics such as classification systems, human excretion, tropic responses, food supply, population dynamics, detailed pollution and biotechnology. Some explanations may include wider single-science context. A 0654-specific objective-by-objective review, Core/Supplement audit, human subject-teacher review, supervised laboratory experience and cumulative assessment remain in progress. Written practice is self-checked and does not predict an official grade. The 2025–2027 syllabus has not been reconciled here; choose the 2028–2029 syllabus only.

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