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IGCSE · Cambridge (CIE) · 0654

Locate amylase secretion and action

Separate salivary and pancreatic sources from the regions receiving them.

Chemical digestion · Cambridge IGCSE 0654 · B7.4

Mapped to the named 0654 section using teaching from the corresponding single-science course. A 0654-specific review of every Core and Supplement objective is still in progress. Written practice is self-checked; it does not demonstrate supervised laboratory competence or award an official Cambridge grade.

Before you begin

  • Recall large and small nutrient molecules, cell membranes and enzyme specificity.
  • Use the stated diagram keys and evidence; models are not to scale.

Work on paper. Try each question before revealing help, and explain why your method works.

Quick readiness check

Which organ secretes saliva containing amylase?

What you will learn

  • Separate salivary and pancreatic sources from the regions receiving them.
  • Explain why enzyme location alone does not prove its secretion source.
Major school-level map: salivary amylase acts in mouth; gastric protease in stomach; pancreatic amylase/protease/lipase in small intestine. Membrane-associated maltase is a separate Extended step.Source is separate from actionsiteSalivary glands → mouthAmylase acts on starchStomach glands → stomachGastric protease acts onproteinPancreas → small intestineAmylase · protease · lipase
Major school-level map: salivary amylase acts in mouth; gastric protease in stomach; pancreatic amylase/protease/lipase in small intestine. Membrane-associated maltase is a separate Extended step.

Two major sources in this model

Salivary glands secrete amylase into the mouth, where starch digestion begins. The pancreas also secretes amylase into the small intestine, where starch breakdown continues. The pancreas is the source organ, not the canal region where its secretion acts.

Amylase does not need to be made in every place where it acts. A secretion can travel through a duct before reaching its substrate. Trace the source → receiving region → substrate in the enzyme-site map.

Conditions matter after secretion

Salivary amylase may continue acting briefly in swallowed material, but stomach acid eventually inactivates it. Do not describe the acidic stomach as the principal amylase environment or the pancreas as a food-filled canal segment.

The simple school map uses mouth and small intestine as the main amylase action regions. It shows sources and action sites rather than all timing, flow and enzyme-concentration detail.

Sources for this lesson

Pause and explain

Where does pancreatic amylase act?

Put the idea to work

Worked example

The pancreas releases amylase through a duct to the duodenum. State the secretion site and action region separately.

Show the worked solution
  1. Secretion source: pancreas.
  2. Receiving/action region: small intestine.
  3. Substrate: starch.

Answer Pancreatic amylase is secreted by pancreas and acts in the small intestine on starch.

Try a topic test

Choose Easy, Normal or Difficult. Save your answers and open worked review after finishing.

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From guided practice to a new situation

Write your answer and reasoning first. Use a hint only if you are stuck. The model solution is for self-checking; your written work is not automatically marked.

1 · Guided

Name the two major amylase secretion sources and their main action regions here.

Give me a hint

Use the source/action map.

Compare my reasoning
  1. Salivary glands → mouth.
  2. Pancreas → small intestine.

Salivary glands: mouth; pancreas: small intestine.

Look for these in your work

  • Both sources.
  • Both regions.
2 · Independent

Correct “the mouth produces all amylase, and pancreatic amylase digests food inside the pancreas”.

Give me a hint

Separate associated glands and canal.

Compare my reasoning
  1. Salivary glands supply mouth.
  2. Pancreas supplies small intestine.

Salivary glands supply amylase to the mouth; pancreas supplies amylase to the small intestine.

Look for these in your work

  • Both errors corrected.
  • Food route remains separate.
3 · Transfer

A diagram gives only the label “amylase in duodenum”. Does it alone identify which organ made that enzyme?

Give me a hint

Action location does not by itself prove source.

Compare my reasoning
  1. Duodenum is the action location.
  2. The source requires the secretion map or further evidence.

The location shows where enzyme is present, not by itself its production source.

Look for these in your work

  • Source/action distinction.
  • Evidence limit.

Common mistakes

  • Source and action site are separate columns.
  • The acidic stomach is not the principal amylase site in this map.
Recall without your notes

What can you explain now?

Where does pancreatic amylase act?

Compare with the explanation

Small intestine.

It is delivered into that canal region.

After trying it yourself, choose your next review. This is your self-assessment.

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Make it stick

Draw source, receiving region and substrate as three separate labels.

If you needed the solution, close it and solve the problem again from a blank page. A correct answer is stronger when you can explain the reason for each step.

Keep learning Sciences — Co-ordinated (Double)

Course scope and assessment

This 2028–2029 pathway maps all 152 detailed subject-content sections in the published 0654 syllabus to original teaching and staged practice. It adapts teaching from the related single-science pathways and excludes clear 0610-only topics such as classification systems, human excretion, tropic responses, food supply, population dynamics, detailed pollution and biotechnology. Some explanations may include wider single-science context. A 0654-specific objective-by-objective review, Core/Supplement audit, human subject-teacher review, supervised laboratory experience and cumulative assessment remain in progress. Written practice is self-checked and does not predict an official grade. The 2025–2027 syllabus has not been reconciled here; choose the 2028–2029 syllabus only.

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