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IGCSE · Cambridge (CIE) · 0654

State the pancreatic source of glucagon

Add the Supplement hormone pairing without replacing pancreatic insulin.

Hormones · Cambridge IGCSE 0654 · B13.2

Mapped to the named 0654 section using teaching from the corresponding single-science course. A 0654-specific review of every Core and Supplement objective is still in progress. Written practice is self-checked; it does not demonstrate supervised laboratory competence or award an official Cambridge grade.

Before you begin

  • Recall electrical impulses, blood transport, gland secretion and the distinction between a stimulus and a body response.

Work on paper. Try each question before revealing help, and explain why your method works.

Quick readiness check

Which gland secretes glucagon?

What you will learn

  • Recall the glucagon source
  • Distinguish two hormones from one gland

State the pancreatic source of glucagon

Supplement: pancreas secretes glucagon as well as the Core hormone insulin. Full glucose feedback control is taught in the separate Homeostasis pathway. Original teaching model.

Hormones model reference
FeatureMeaning
GlucagonPancreas → blood-borne hormone
InsulinRetained Core pancreatic hormone
AdrenalineAdrenal source, not the glucagon source
Next pathwayHomeostasis control remains separate

Recall the glucagon source

Glucagon is secreted by the pancreas. This Supplement requirement adds a second pancreatic hormone to the Core pancreas–insulin pairing. The same gland can produce more than one hormone, so learning glucagon does not mean insulin is no longer pancreatic. Both are chemical signals released into blood rather than electrical impulses carried along neurones.

Glucagon and insulin have different names and different roles. As background for the next pathway, glucagon contributes to raising blood glucose, whereas insulin contributes to lowering it. The detailed liver control and negative-feedback explanation belong to Homeostasis and remain a separate sequence; this requirement specifically asks for the pancreatic source of glucagon.

Distinguish two hormones from one gland

Adrenaline is another hormone that can raise blood glucose in the taught fight-or-flight account, but it is secreted by adrenal glands rather than being the required pancreatic glucagon pairing. A shared direction of an effect does not prove a shared source or make two chemical names interchangeable. Start a source question by naming the gland.

If a diagram identifies the elongated upper-abdominal pancreas, give insulin for its required Core pairing and glucagon when the Supplement question asks for this additional hormone. Do not select a digestive enzyme from pancreatic juice. A blood-borne hormone and an enzyme delivered through a digestive duct are different categories of pancreatic output.

Sources for this lesson

Pause and explain

Which pancreatic account retains both requirements?

Put the idea to work

Worked example

State the source of glucagon and retain the Core pancreatic pairing.

Show the worked solution
  1. Pancreas secretes glucagon.
  2. Pancreas also secretes insulin.

Answer Glucagon is secreted by the pancreas; the Core pancreatic pairing insulin remains correct.

Try a topic test

Choose Easy, Normal or Difficult. Save your answers and open worked review after finishing.

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From guided practice to a new situation

Write your answer and reasoning first. Use a hint only if you are stuck. The model solution is for self-checking; your written work is not automatically marked.

1 · Guided

State which gland secretes glucagon.

Give me a hint

Recall the additional pancreatic hormone.

Compare my reasoning
  1. Identify pancreas as the gland.
  2. Glucagon is a chemical hormone released into blood.

Glucagon is secreted by the pancreas.

Look for these in your work

  • Name pancreas
  • Keep hormone and gland distinct
2 · Independent

Give the Core and added Supplement pancreatic hormone names.

Give me a hint

One source can produce two hormones.

Compare my reasoning
  1. Core pairing: insulin.
  2. Added Supplement pairing: glucagon.

Pancreas secretes insulin and glucagon.

Look for these in your work

  • Retain insulin
  • Add glucagon
3 · Transfer

A learner assigns both adrenaline and glucagon to adrenal glands because both can raise blood glucose. Correct the sources.

Give me a hint

Similar effects do not establish the same producer.

Compare my reasoning
  1. Adrenal glands secrete adrenaline.
  2. Pancreas secretes glucagon.

Adrenaline: adrenal glands. Glucagon: pancreas. A shared blood-glucose direction does not imply a shared gland source.

Look for these in your work

  • Correct both sources
  • Explain why effect similarity is insufficient

Common mistakes

  • Assigning glucagon to adrenal glands.
  • Replacing insulin with glucagon in every Core pairing answer.
Recall without your notes

What can you explain now?

Which pancreatic account retains both requirements?

Compare with the explanation

Pancreas secretes insulin and glucagon

The Supplement addition does not replace the Core hormone.

After trying it yourself, choose your next review. This is your self-assessment.

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Make it stick

Recall pancreas as the glucagon source and retain the insulin pairing.

If you needed the solution, close it and solve the problem again from a blank page. A correct answer is stronger when you can explain the reason for each step.

Keep learning Sciences — Co-ordinated (Double)

Course scope and assessment

This 2028–2029 pathway maps all 152 detailed subject-content sections in the published 0654 syllabus to original teaching and staged practice. It adapts teaching from the related single-science pathways and excludes clear 0610-only topics such as classification systems, human excretion, tropic responses, food supply, population dynamics, detailed pollution and biotechnology. Some explanations may include wider single-science context. A 0654-specific objective-by-objective review, Core/Supplement audit, human subject-teacher review, supervised laboratory experience and cumulative assessment remain in progress. Written practice is self-checked and does not predict an official grade. The 2025–2027 syllabus has not been reconciled here; choose the 2028–2029 syllabus only.

StudyForA · Learn with understanding

Original teaching content and links to official sources. Check your exam year and qualification before using a resource.