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IGCSE · Cambridge (CIE) · 0970

Explain separation of chromosome copies into complete daughter complements

A copied A B C complement separates into A B C in each daughter. Equal totals do not rescue a distribution with a missing or duplicated chromosome identity.

Mitosis pathway · 0970 (9–1) · 17.2
Exam scope and assessment notes

Extended only (Supplement) · Biology 0970, 2026–2028. Use the stated specimen features and evidence. Diagrams are schematic. Written practice is self-checked; human subject-teacher review, supervised practical competence and cumulative assessment remain pending. Cambridge states that IGCSE 0970 has the same subject content as IGCSE 0610, with 9–1 grading. This StudyForA pathway maps the 2026–2028 syllabus only. This 9–1 graded qualification is available only in a limited number of administrative zones. Confirm that your centre can enter you for this code and exam series with Cambridge International. Cambridge has published a separate syllabus for 2029. StudyForA has not reconciled that version yet; this page supports exams in 2026, 2027 and 2028 only.

Before you begin

  • Recall chromosomes, genes, chromosome sets, selective gene expression and the distinction between a nucleus and a whole cell.

Work on paper. Try each question before revealing help, and explain why your method works.

Quick readiness check

What is the expected normal distribution of copied A B C chromosomes?

What you will learn

  • Distribute every chromosome identity
  • Recognise a missing or duplicate product

Original teaching model. Counts and records are stipulated; drawings are schematic.

Explain separation of chromosome copies into complete daughter complementsA copied A B C complement separates into A B C in each daughter. Equal totals do not rescue a distribution with a missing or duplicated chromosome identity.Supplied chromosome identitiesBefore copying: 3 chromosomesABCExact copying before mitosisABC3 replicated chromosomes; 6 DNA moleculesCopies separateduring mitosisABCABCDaughter 1: 3Daughter 2: 3Every original identity in EACHdaughterBoxes are nuclei; cell division usually follows
A copied A B C complement separates into A B C in each daughter. Equal totals do not rescue a distribution with a missing or duplicated chromosome identity.
Division, chromosome count and cell-state key
FeatureMeaning
Normal daughter 1A, B and C
Normal daughter 2A, B and C
Faulty counterexampleA A B / B C C: missing identities
LimitThree labels alone do not establish ploidy

Distribute every chromosome identity

During mitosis, the chromosome copies separate so each daughter nucleus receives the complete complement. In the original three-label model, chromosomes A, B and C have each been copied before division. One copy of A, one of B and one of C must go to each daughter. It is not enough for the total across both products to contain six objects if their distribution is incomplete.

The two products A B C and A B C retain the original three-chromosome list. A hypothetical faulty distribution A A B and B C C also totals six objects, but neither product contains the complete original list. That record is a counterexample to normal accurate mitosis, not an alternative normal method of chromosome maintenance.

Recognise a missing or duplicate product

This model specifies three labelled chromosomes without supplying a diploid or haploid set classification. The number three alone cannot establish its ploidy. It simply lets you check identity, completeness and count. The later diploid model supplies the chromosome-set information needed to show maintenance of both sets as well as the individual chromosome number.

Copies that have separated are counted as daughter chromosomes. The completed daughter nuclei provide the comparable endpoint for the parent-to-product count. Within one not-yet-divided cell during separation, the combined chromosome count is a different question. Do not mix that temporary combined quantity with the maintained number in each final daughter nucleus.

Pause and explain

A A B and B C C total six chromosome objects. Does that establish normal distribution?

Put the idea to work

Worked example

Which daughter lists preserve A B C: A B C / A B C or A A B / B C C?

Show the worked solution
  1. Compare every identity in each product.
  2. Do not rely only on the combined total.

Answer A B C in both daughters preserves the complete complement; the other distribution has missing and duplicate identities.

Try a topic test

Choose Easy, Normal or Difficult. Save your answers and open worked review after finishing.

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From guided practice to a new situation

Write your answer and reasoning first. Use a hint only if you are stuck. The model solution is for self-checking; your written work is not automatically marked.

1 · Guided

Explain the normal separation of copied A B C chromosomes.

Give me a hint

Give every identity to each daughter.

Compare my reasoning
  1. Identify two copies of each original chromosome.
  2. Assign one of each to both products.

One A, one B and one C copy go to each daughter nucleus, giving A B C in both and maintaining the original number three.

Look for these in your work

  • Distribute all identities
  • State the per-daughter number
2 · Independent

Compare correct A B C / A B C with faulty A A B / B C C distributions.

Give me a hint

Check completeness as well as totals.

Compare my reasoning
  1. Count three in each product.
  2. Compare each list with A B C.

Both distributions total six objects, but only A B C / A B C gives every identity to each daughter. A A B lacks C; B C C lacks A.

Look for these in your work

  • Check both daughters
  • Identify the missing entries
3 · Transfer

A three-chromosome diagram has no chromosome-type or set key. Can its number alone show that it is haploid?

Give me a hint

A set must be defined.

Compare my reasoning
  1. Identify that only a total is supplied.
  2. State the absent set or type information.

No. The total three does not establish haploid status without information about a complete set or the chromosome types.

Look for these in your work

  • Distinguish number and ploidy
  • State the evidence limit

Common mistakes

  • A combined total can conceal faulty distribution.
  • A count alone does not specify chromosome sets.
Recall without your notes

What can you explain now?

A A B and B C C total six chromosome objects. Does that establish normal distribution?

Compare with the explanation

No; each daughter has a missing and a duplicated identity

Check every complement separately.

After trying it yourself, choose your next review. This is your self-assessment.

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Make it stick

Without your notes, distribute every chromosome identity and recognise a missing or duplicate product. Distinguish nuclear division, chromosome copies and completed daughter cells before opening the solutions.

If you needed the solution, close it and solve the problem again from a blank page. A correct answer is stronger when you can explain the reason for each step.

Keep learning Biology (9-1)

Course scope and assessment

780 sequenced lessons provide 2340 guided, independent and application problems in characteristics, classification, cells, organisation, specimen size, membrane transport, biological molecules, enzymes, plant and human nutrition, plant transport, circulatory systems, the heart, blood vessels, blood, disease transmission, body defences, immunity, gas exchange in humans, respiration energy uses and investigations, aerobic respiration, anaerobic respiration and recovery, excretion in humans, coordination and response, sense organs, hormones, homeostasis, tropic responses, drugs, asexual reproduction, sexual reproduction, sexual reproduction in plants, sexual reproduction in humans, sex hormones in humans, sexually transmitted infections, chromosomes, genes and proteins, mitosis, meiosis, monohybrid inheritance, variation, adaptive features, selection, energy flow, food chains and webs, nutrient cycles, population, community, ecosystem, population-growth phases, food supply, habitat destruction, pollution, conservation, biotechnology and genetic modification. 61 of 61 syllabus sections have linked teaching and staged practice. The earlier inheritance overview remains introductory, and the monohybrid pathway develops the relevant Core and Supplement requirements. This is not full programme completion or guaranteed exam readiness. Written practice is self-checked. This is the separate 9–1 qualification 0970; Cambridge states that its 2026–2028 subject content is otherwise the same as 0610. This 9–1 graded qualification is available only in a limited number of administrative zones. Confirm that your centre can enter you for this code and exam series with Cambridge International. The 2029 syllabus is separately published at https://www.cambridgeinternational.org/Images/764352-2029-syllabus.pdf and is not yet mapped here. This course supports exams in 2026, 2027 and 2028 only.

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