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IGCSE · Cambridge (CIE) · 0970

Keep the gene in the nucleus while its information is used

The original gene remains as nuclear DNA. mRNA, not a moved chromosome segment, carries the information toward protein assembly in the cytoplasm.

Chromosomes, genes and proteins pathway · 0970 (9–1) · 17.1
Exam scope and assessment notes

Extended only (Supplement) · Biology 0970, 2026–2028. Use the stated specimen features and evidence. Diagrams are schematic. Written practice is self-checked; human subject-teacher review, supervised practical competence and cumulative assessment remain pending. Cambridge states that IGCSE 0970 has the same subject content as IGCSE 0610, with 9–1 grading. This StudyForA pathway maps the 2026–2028 syllabus only. This 9–1 graded qualification is available only in a limited number of administrative zones. Confirm that your centre can enter you for this code and exam series with Cambridge International. Cambridge has published a separate syllabus for 2029. StudyForA has not reconciled that version yet; this page supports exams in 2026, 2027 and 2028 only.

Before you begin

  • Recall the nucleus, DNA base pairing, gametes, fertilisation, enzymes, membrane carriers and chemical synapses.

Work on paper. Try each question before revealing help, and explain why your method works.

Quick readiness check

Where does the protein-coding gene remain in the stated cell model?

What you will learn

  • Separate the location of DNA from its information copy
  • Reject a whole-gene movement or material-conversion model

Original teaching model. Counts and records are stipulated; drawings are schematic.

Keep the gene in the nucleus while its information is usedThe original gene remains as nuclear DNA. mRNA, not a moved chromosome segment, carries the information toward protein assembly in the cytoplasm.NucleusDNA geneRemains heremRNA copyMade heremRNA moves to cytoplasmCytoplasmmRNABase orderRibosomeAmino acidsOrdered amino-acid chainmRNA bases determine product orderDNA and RNA are not the product material
The original gene remains as nuclear DNA. mRNA, not a moved chromosome segment, carries the information toward protein assembly in the cytoplasm.
Information, material and count key
FeatureMeaning
SourceDNA gene in the nucleus
MessagemRNA information copy
MovementMessage reaches the cytoplasm
BoundaryGene stays nuclear in this model

Separate the location of DNA from its information copy

In the plant or animal cell model used here, the DNA gene coding for a protein remains in the nucleus. Protein production uses information from that gene without moving the whole gene out to a ribosome. This is the first boundary in the required Extended sequence: the original nuclear information is distinct from the message that later reaches the cytoplasm.

An mRNA molecule is made using the gene’s information. It serves as a message copy in the limited syllabus model, while the DNA region remains part of its chromosome. The cell does not remove a chromosome segment each time a protein is made, and making a message does not convert the nuclear gene into the finished protein.

Reject a whole-gene movement or material-conversion model

The original two-location diagram keeps the DNA label inside a nuclear boundary and places a message arrow across to the cytoplasm. The arrow represents movement of mRNA information, not export of the DNA chromosome. This distinguishes the source from its copy and helps prevent an incorrect answer saying the gene passes through the ribosome.

The lesson covers the stated nuclear cell model. Not every organism or cell has this organisation; the earlier prokaryote lesson explained a different arrangement. The Cambridge requirement here is the bounded production sequence in the supplied nucleus-and-cytoplasm setting, without detailed mechanisms of transcription or translation.

Pause and explain

What crosses to the cytoplasm in the required sequence?

Put the idea to work

Worked example

A diagram moves the chromosome into a ribosome. What should move instead?

Show the worked solution
  1. Keep the DNA gene in the nucleus.
  2. Use an mRNA information copy moving to the cytoplasm.

Answer The gene remains in the nucleus; mRNA carries its information to the cytoplasm and passes through the ribosome.

Try a topic test

Choose Easy, Normal or Difficult. Save your answers and open worked review after finishing.

Test this topic →

From guided practice to a new situation

Write your answer and reasoning first. Use a hint only if you are stuck. The model solution is for self-checking; your written work is not automatically marked.

1 · Guided

State where the original gene remains during the required protein-production sequence.

Give me a hint

Distinguish source from copy.

Compare my reasoning
  1. Identify the DNA gene.
  2. Keep it in the nucleus.

The DNA gene coding for the protein remains in the nucleus.

Look for these in your work

  • Name original DNA
  • Give nuclear location
2 · Independent

Correct a model that sends the original gene through a ribosome.

Give me a hint

Change the moving label without changing the source location.

Compare my reasoning
  1. Keep the gene in the nucleus.
  2. Replace the exported label with mRNA.

The gene stays in the nucleus; an mRNA information copy moves to the cytoplasm and passes through ribosomes.

Look for these in your work

  • Repair the source location
  • Repair the moving molecule
3 · Transfer

A record shows three messages made from a gene. Does it establish the gene was removed three times?

Give me a hint

Making copies does not consume the source.

Compare my reasoning
  1. Identify message copies as distinct molecules.
  2. Retain the original DNA in the nuclear model.

No. Three mRNA messages can use the same source information; the record does not mean the DNA gene was removed or consumed.

Look for these in your work

  • Distinguish source and copies
  • Reject gene consumption

Common mistakes

  • The original DNA gene does not leave for the ribosome.
  • An information copy is not the original chromosome.
Recall without your notes

What can you explain now?

What crosses to the cytoplasm in the required sequence?

Compare with the explanation

mRNA carrying the information copy

It links nuclear information with ribosome assembly.

After trying it yourself, choose your next review. This is your self-assessment.

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Make it stick

Explain separate the location of DNA from its information copy and reject a whole-gene movement or material-conversion model. Use the stated cell, chromosome sets and information pathway before opening the solutions.

If you needed the solution, close it and solve the problem again from a blank page. A correct answer is stronger when you can explain the reason for each step.

Keep learning Biology (9-1)

Course scope and assessment

780 sequenced lessons provide 2340 guided, independent and application problems in characteristics, classification, cells, organisation, specimen size, membrane transport, biological molecules, enzymes, plant and human nutrition, plant transport, circulatory systems, the heart, blood vessels, blood, disease transmission, body defences, immunity, gas exchange in humans, respiration energy uses and investigations, aerobic respiration, anaerobic respiration and recovery, excretion in humans, coordination and response, sense organs, hormones, homeostasis, tropic responses, drugs, asexual reproduction, sexual reproduction, sexual reproduction in plants, sexual reproduction in humans, sex hormones in humans, sexually transmitted infections, chromosomes, genes and proteins, mitosis, meiosis, monohybrid inheritance, variation, adaptive features, selection, energy flow, food chains and webs, nutrient cycles, population, community, ecosystem, population-growth phases, food supply, habitat destruction, pollution, conservation, biotechnology and genetic modification. 61 of 61 syllabus sections have linked teaching and staged practice. The earlier inheritance overview remains introductory, and the monohybrid pathway develops the relevant Core and Supplement requirements. This is not full programme completion or guaranteed exam readiness. Written practice is self-checked. This is the separate 9–1 qualification 0970; Cambridge states that its 2026–2028 subject content is otherwise the same as 0610. This 9–1 graded qualification is available only in a limited number of administrative zones. Confirm that your centre can enter you for this code and exam series with Cambridge International. The 2029 syllabus is separately published at https://www.cambridgeinternational.org/Images/764352-2029-syllabus.pdf and is not yet mapped here. This course supports exams in 2026, 2027 and 2028 only.

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