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IGCSE · Cambridge (CIE) · 0610

Apply dominant and recessive allele expression in a one-gene model

Dominance is an expression rule, not a statement of frequency, value or allele deletion.

Monohybrid inheritance pathway · 17.4

Core and Extended; Biology 0610, 2026–2028. Use the stated specimen features and evidence. Diagrams are schematic. Written practice is self-checked

Before you begin

  • Recall chromosomes, genes and alleles, meiosis, haploid gametes and fertilisation restoring two chromosome sets.

Work on paper. Try each question before revealing help, and explain why your method works.

Quick readiness check

What does Tt contain?

What you will learn

  • Use the supplied dominant expression rule
  • Identify when the recessive phenotype is expressed

Original teaching model. Pedigrees and records are fictional; allele and probability assumptions are stated.

Apply dominant and recessive allele expression in a one-gene modelDominance is an expression rule, not a statement of frequency, value or allele deletion.TTDominant allele present; pigmentpresentTtDominant phenotype; t still carriedttNo dominant allele; recessivephenotypePopulation frequencyA separate question from dominance
Dominance is an expression rule, not a statement of frequency, value or allele deletion.
Allele, phenotype and evidence key
FeatureMeaning
TTDominant allele present; pigment present
TtDominant phenotype; t still carried
ttNo dominant allele; recessive phenotype
Population frequencyA separate question from dominance

Use the supplied dominant expression rule

In the simple complete-dominance model used here, a dominant allele is expressed in the phenotype if it is present in the genotype. The original key states that T produces pigment when present. TT and Tt therefore both show pigment. Dominant describes the expression relationship at this gene, not whether the allele is common, beneficial, stronger or more desirable.

A recessive allele is expressed in the phenotype only when no dominant allele of that gene is present in this model. The key uses t for pigment absence, so tt lacks pigment. Tt still carries and can transmit t even though the phenotype shows the T-associated feature. The recessive allele has not disappeared from the genotype and is not prevented from entering a gamete.

Identify when the recessive phenotype is expressed

Read the question’s key before converting genotypes to phenotypes. Letter case is a convenient notation in the simple model; it does not create the biological rule. Other inheritance patterns require their own rules, including codominance in the Supplement sequence. Do not describe every heterozygote in biology as showing only one allele’s contribution.

Apply the two rules in order: check the allele pair, find whether a dominant allele is present, then give the stated phenotype. For a supplied set TT, Tt, tt and tt, two show pigment and two do not. That record gives a one-to-one observed count, but it does not establish the parents’ genotypes or a universal frequency of either allele. Expression and population frequency are different questions.

Pause and explain

When is the recessive phenotype expressed under the supplied rule?

Put the idea to work

Worked example

With T dominant for pigment and t recessive for absence, classify TT, Tt and tt.

Show the worked solution
  1. Look for T in each allele pair: TT and Tt both contain it, whereas tt does not.
  2. Use the expression key to assign pigment or absence. Retain the t in Tt even though its recessive feature is not expressed.

Answer Given T produces pigment whenever present: TT and Tt show pigment; tt does not. Tt still contains and can transmit t.

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From guided practice to a new situation

Write your answer and reasoning first. Use a hint only if you are stuck. The model solution is for self-checking; your written work is not automatically marked.

1 · Guided

Assign pigment phenotypes to TT, Tt and tt using the supplied rule. Explain why Tt does not show pigment absence.

Give me a hint

First check whether T is present.

Compare my reasoning
  1. Identify T in TT and Tt.
  2. Identify its absence in tt.
  3. Apply the stated expression rule.

TT and Tt show pigment; tt lacks pigment. Tt has the dominant allele T, so the recessive absence phenotype is not expressed under this rule.

Look for these in your work

  • Three correct phenotypes
  • Uses presence of T to explain Tt
2 · Independent

A population record says t is more frequent than T. Does this make t dominant? Explain using the definition.

Give me a hint

Frequency and phenotype expression describe different properties.

Compare my reasoning
  1. Identify the frequency statement.
  2. Recall the supplied expression rule.

No. Dominance concerns expression when the allele is present with its alternative in the genotype. The relative frequency of t does not change the stated T/t expression rule.

Look for these in your work

  • Rejects frequency as definition
  • Explains genotype-expression relationship
3 · Transfer

In a supplied record TT, Tt, tt, tt, calculate pigment present to absent and explain why this record alone does not identify a parental cross.

Give me a hint

Assign each phenotype before counting.

Compare my reasoning
  1. Count two pigment-present and two pigment-absent records.
  2. Simplify two to two.
  3. Distinguish observed records from known parent genotypes.

The observed count ratio is 2:2, simplified to 1:1. It does not by itself establish a parental cross; parental genotypes and the transmission model would need to be supplied or investigated.

Look for these in your work

  • Correct 1:1 observed ratio
  • Avoids identifying parents from the record alone

Common mistakes

  • Calling dominant common or biologically better
  • Saying t is absent from Tt because its feature is not expressed
  • Applying complete dominance when a different expression rule is supplied
Recall without your notes

What can you explain now?

When is the recessive phenotype expressed under the supplied rule?

Compare with the explanation

When no dominant allele of this gene is present

tt has no T and expresses the recessive feature in this model.

After trying it yourself, choose your next review. This is your self-assessment.

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Make it stick

Without your notes, use the supplied dominant expression rule and identify when the recessive phenotype is expressed. Use the supplied allele key and state what the evidence can establish.

If you needed the solution, close it and solve the problem again from a blank page. A correct answer is stronger when you can explain the reason for each step.

Keep learning Biology

Course scope and assessment

780 sequenced lessons provide 2340 guided, independent and application problems in characteristics, classification, cells, organisation, specimen size, membrane transport, biological molecules, enzymes, plant and human nutrition, plant transport, circulatory systems, the heart, blood vessels, blood, disease transmission, body defences, immunity, gas exchange in humans, respiration energy uses and investigations, aerobic respiration, anaerobic respiration and recovery, excretion in humans, coordination and response, sense organs, hormones, homeostasis, tropic responses, drugs, asexual reproduction, sexual reproduction, sexual reproduction in plants, sexual reproduction in humans, sex hormones in humans, sexually transmitted infections, chromosomes, genes and proteins, mitosis, meiosis, monohybrid inheritance, variation, adaptive features, selection, energy flow, food chains and webs, nutrient cycles, population, community, ecosystem, population-growth phases, food supply, habitat destruction, pollution, conservation, biotechnology and genetic modification. 61 of 61 syllabus sections have linked teaching and staged practice. The earlier inheritance overview remains introductory, and the monohybrid pathway develops the relevant Core and Supplement requirements. This is not full programme completion or guaranteed exam readiness. Written practice is self-checked.

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