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IGCSE · Cambridge (CIE) · 0610

State the exchange functions of capillaries

Connect blood transport with delivery to cells and removal of their wastes.

Blood vessels pathway · 9.3

Core and Extended; Biology 0610, 2026–2028. Use the stated specimen features and evidence. Diagrams are schematic. Written practice is self-checked

Before you begin

  • Recall diffusion and respiration.

Work on paper. Try each question before revealing help, and explain why your method works.

Quick readiness check

Which vessel is the main local exchange surface?

What you will learn

  • Delivery ends at a tissue exchange surface
  • Distinguish body exchange from lung exchange
At the supplied respiring tissue, oxygen and glucose are delivered from blood, while carbon dioxide moves into blood. Arrows represent net movement, not whole-cell passage.Body-tissue exchangeBlood → cellsOxygen and nutrientsCells → bloodCarbon dioxide and wastesWithin lumenRed blood cells remain
At the supplied respiring tissue, oxygen and glucose are delivered from blood, while carbon dioxide moves into blood. Arrows represent net movement, not whole-cell passage. Original schematic, not to scale.

Delivery ends at a tissue exchange surface

Capillaries form networks close to body cells. They allow exchange between blood and tissues: oxygen and nutrients such as glucose can move from blood towards cells, while carbon dioxide and other wastes can move from cells towards blood. The heart transports blood around the system; a capillary network connects that transport with local exchange.

For oxygen in a respiring body tissue, the supplied model shows a higher concentration on the blood side than the cell side. Net diffusion follows that gradient. Carbon dioxide produced by respiration has the opposite net direction in this model. Do not assume every substance moves in the same direction at every organ.

Distinguish body exchange from lung exchange

At the lungs, oxygen moves into the blood from the air-exchange surface and carbon dioxide moves out of blood towards the air. Capillaries still carry out exchange, but the directions differ from a respiring body tissue. Use the stated location and gradient rather than memorising that oxygen always leaves blood.

Blood cells normally remain in the capillary lumen during this exchange model. Oxygen and dissolved substances cross the wall; whole red blood cells do not routinely pass through it into tissues. The schematic is for explaining exchange, not for calculating real vessel dimensions or diagnosing a specimen.

Pause and explain

What is the net oxygen direction at the supplied respiring body tissue?

Put the idea to work

Worked example

At a supplied body tissue, oxygen is more concentrated in blood and carbon dioxide in cells. State both net movements.

Show the worked solution
  1. Oxygen moves down its gradient from blood towards cells.
  2. Carbon dioxide moves down its gradient from cells towards blood.

Answer Oxygen: blood → cells. Carbon dioxide: cells → blood.

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Choose Easy, Normal or Difficult. Save your answers and open worked review after finishing.

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From guided practice to a new situation

Write your answer and reasoning first. Use a hint only if you are stuck. The model solution is for self-checking; your written work is not automatically marked.

1 · Guided

State two materials delivered from blood to body cells in this model.

Give me a hint

Choose respiration materials.

Compare my reasoning
  1. Oxygen is delivered for aerobic respiration.
  2. Glucose is a transported nutrient used by cells.

Oxygen and glucose.

Look for these in your work

  • Name oxygen
  • Name a nutrient
2 · Independent

State the movement of carbon dioxide at body tissue and at lungs.

Give me a hint

Identify where carbon dioxide is produced and removed.

Compare my reasoning
  1. Respiring body cells produce carbon dioxide.
  2. At lungs it moves from blood towards the air-exchange surface.

Body: cells → blood. Lungs: blood → air-exchange surface.

Look for these in your work

  • Distinguish the two locations
  • Give both directions
3 · Transfer

Why is “capillaries release whole red blood cells to feed tissues” incorrect?

Give me a hint

Separate the carrier from the material it carries.

Compare my reasoning
  1. Red blood cells normally stay within the lumen.
  2. Oxygen and dissolved nutrients cross the capillary wall towards cells.

Capillaries exchange oxygen and dissolved materials; red blood cells normally remain in the blood.

Look for these in your work

  • Keep cells within the lumen
  • Describe exchanged materials

Common mistakes

  • Saying every substance leaves blood.
  • Making red blood cells normally leave the lumen.
Recall without your notes

What can you explain now?

What is the net oxygen direction at the supplied respiring body tissue?

Compare with the explanation

Blood → cells

The supplied oxygen gradient favours delivery.

After trying it yourself, choose your next review. This is your self-assessment.

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Make it stick

Trace oxygen and carbon dioxide across a body-tissue capillary, then reverse the context to lungs.

If you needed the solution, close it and solve the problem again from a blank page. A correct answer is stronger when you can explain the reason for each step.

Keep learning Biology

Course scope and assessment

780 sequenced lessons provide 2340 guided, independent and application problems in characteristics, classification, cells, organisation, specimen size, membrane transport, biological molecules, enzymes, plant and human nutrition, plant transport, circulatory systems, the heart, blood vessels, blood, disease transmission, body defences, immunity, gas exchange in humans, respiration energy uses and investigations, aerobic respiration, anaerobic respiration and recovery, excretion in humans, coordination and response, sense organs, hormones, homeostasis, tropic responses, drugs, asexual reproduction, sexual reproduction, sexual reproduction in plants, sexual reproduction in humans, sex hormones in humans, sexually transmitted infections, chromosomes, genes and proteins, mitosis, meiosis, monohybrid inheritance, variation, adaptive features, selection, energy flow, food chains and webs, nutrient cycles, population, community, ecosystem, population-growth phases, food supply, habitat destruction, pollution, conservation, biotechnology and genetic modification. 61 of 61 syllabus sections have linked teaching and staged practice. The earlier inheritance overview remains introductory, and the monohybrid pathway develops the relevant Core and Supplement requirements. This is not full programme completion or guaranteed exam readiness. Written practice is self-checked.

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