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IGCSE · Cambridge (CIE) · 0610

Connect kidney processing with blood and urine routes

Follow the materials without turning a urine tube into a blood vessel.

Excretion in humans pathway · 13.1

Extended only (Supplement); Biology 0610, 2026–2028. Use the stated specimen features and evidence. Diagrams are schematic. Written practice is self-checked

Before you begin

  • Recall cell metabolism, blood transport, amino acids and the distinction between excretion and egestion.

Work on paper. Try each question before revealing help, and explain why your method works.

Quick readiness check

Which carries urine from a kidney to the bladder?

What you will learn

  • Connect organ and nephron scales
  • Trace the route of one stated material

Connect kidney processing with blood and urine routes

Organ and nephron scales are connected but distinct. Blood supplies and receives substances; urine travels along ureter, bladder and urethra. Original teaching model.

Excretion model reference
FeatureMeaning
Blood routeKidney circulation and glomerular network
FiltrationBlood → initial nephron contents
ReabsorptionNephron contents → associated blood vessels
Urine routeKidney → ureter → bladder → urethra

Connect organ and nephron scales

At organ scale, the renal blood supply brings blood into a kidney and carries blood away. At nephron scale, blood passes through a glomerular capillary network where filtration begins. Associated blood vessels receive reabsorbed materials from the tubule contents. Blood circulation and the urine route connect at processing stages but are not one continuous tube.

A glucose molecule in the normal outline can pass from glomerular blood into the initial filtrate and then return from the nephron to blood by reabsorption. It does not have to travel into a ureter before returning, and it is not manufactured by the bladder. This route makes clear why filtration can include useful materials while final urine differs from the initial mixture.

Trace the route of one stated material

A water portion that is not returned can contribute to final urine containing urea and excess ions. Urine passes from the kidney along a ureter, reaches the bladder for storage and leaves through the urethra. These named urinary structures are distinct from the renal vessels and the microscopic glomerulus and associated capillaries.

A route drawing shows organisation and directions, not the fraction of every blood constituent leaving at each point. The outline does not establish a fixed percentage of urea removal on one pass or require detailed transport mechanisms. Use the named stages and normal reabsorption quantities, and restrict any numerical conclusion to the amounts and boundaries actually supplied.

Pause and explain

Which route correctly describes reabsorption?

Put the idea to work

Worked example

Trace normally filtered glucose back to blood.

Show the worked solution
  1. Glomerular filtration puts glucose into initial nephron contents.
  2. Nephron reabsorption returns all filtered glucose to associated blood vessels.

Answer Blood → initial filtrate → reabsorption → blood, in the normal outline.

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Choose Easy, Normal or Difficult. Save your answers and open worked review after finishing.

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From guided practice to a new situation

Write your answer and reasoning first. Use a hint only if you are stuck. The model solution is for self-checking; your written work is not automatically marked.

1 · Guided

Trace glucose filtration and return using the normal outline.

Give me a hint

Show the two directions in order.

Compare my reasoning
  1. Blood glucose enters initial filtrate at the glomerulus.
  2. All filtered glucose returns from nephron contents to blood.

Glomerular blood → initial filtrate → nephron reabsorption → associated blood vessels, with all filtered glucose returned in the normal outline.

Look for these in your work

  • Include both processing stages
  • Retain all-glucose return
2 · Independent

Trace urine from its kidney origin to outside the body.

Give me a hint

Use the organ-scale route.

Compare my reasoning
  1. Urine passes into a ureter then bladder.
  2. It exits through the urethra.

Kidney → ureter → bladder → urethra → outside.

Look for these in your work

  • Name both urinary tubes
  • Keep the bladder between them
3 · Transfer

A drawing uses one line for renal vein and ureter. Explain the error.

Give me a hint

Compare the transported fluid and destination.

Compare my reasoning
  1. Renal vein returns blood to circulation.
  2. Ureter carries urine to bladder.

They are separate routes: renal vein carries blood away, while ureter carries urine to the bladder; one line obscures their different fluids and destinations.

Look for these in your work

  • Distinguish fluids
  • Distinguish destinations

Common mistakes

  • Sending reabsorbed glucose through the ureter first.
  • Equating glomerulus with bladder.
Recall without your notes

What can you explain now?

Which route correctly describes reabsorption?

Compare with the explanation

Nephron contents back into blood

Useful filtered materials return.

After trying it yourself, choose your next review. This is your self-assessment.

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Make it stick

Trace both blood processing and the separate urine route without mixing tubes.

If you needed the solution, close it and solve the problem again from a blank page. A correct answer is stronger when you can explain the reason for each step.

Keep learning Biology

Course scope and assessment

780 sequenced lessons provide 2340 guided, independent and application problems in characteristics, classification, cells, organisation, specimen size, membrane transport, biological molecules, enzymes, plant and human nutrition, plant transport, circulatory systems, the heart, blood vessels, blood, disease transmission, body defences, immunity, gas exchange in humans, respiration energy uses and investigations, aerobic respiration, anaerobic respiration and recovery, excretion in humans, coordination and response, sense organs, hormones, homeostasis, tropic responses, drugs, asexual reproduction, sexual reproduction, sexual reproduction in plants, sexual reproduction in humans, sex hormones in humans, sexually transmitted infections, chromosomes, genes and proteins, mitosis, meiosis, monohybrid inheritance, variation, adaptive features, selection, energy flow, food chains and webs, nutrient cycles, population, community, ecosystem, population-growth phases, food supply, habitat destruction, pollution, conservation, biotechnology and genetic modification. 61 of 61 syllabus sections have linked teaching and staged practice. The earlier inheritance overview remains introductory, and the monohybrid pathway develops the relevant Core and Supplement requirements. This is not full programme completion or guaranteed exam readiness. Written practice is self-checked.

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Original teaching content and links to official sources. Check your exam year and qualification before using a resource.