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IGCSE · Cambridge (CIE) · 0610

Describe antibiotic resistance in bacteria

Assign resistance to the bacterium and the specified drug.

Drugs pathway · 15.1

Core and Extended; Biology 0610, 2026–2028. Use the stated specimen features and evidence. Diagrams are schematic. Written practice is self-checked

Before you begin

  • Distinguish bacteria from viruses; recall enzymes, chemical reactions, pathogens and reproduction of bacteria.

Work on paper. Try each question before revealing help, and explain why your method works.

Quick readiness check

Which entity is antibiotic-resistant in this account?

What you will learn

  • Identify survival despite a particular antibacterial treatment
  • Explain reduced effectiveness without claiming resistance to every drug

Describe antibiotic resistance in bacteria

Resistance belongs to bacteria and is assessed relative to a specified antibiotic. Surviving resistant bacteria reduce that drug’s effectiveness; other drugs need separate evidence.Susceptible strain · antibiotic ASpecified drug affects the bacteriaEffectiveness depends on targetand susceptibilityResistant strain · antibiotic ABacteria can survive or growResistance belongs to bacteriaOther antibiotics need evidence
Resistance belongs to bacteria and is assessed relative to a specified antibiotic. Surviving resistant bacteria reduce that drug’s effectiveness; other drugs need separate evidence. Original teaching model.
Drug and antibiotic model reference
FeatureMeaning
Susceptible strainControlled by the specified antibiotic
Resistant strainCan survive or grow despite that antibiotic
ConsequenceReduced drug effectiveness against that strain
Not impliedHost-body resistance or resistance to every other antibiotic

Further reading: CDC explanation of antimicrobial resistance.

Identify survival despite a particular antibacterial treatment

Some bacteria are resistant to particular antibiotics. Resistance means that the specified antibiotic does not control those bacteria as expected, so they can survive or continue growing under the relevant conditions. The resistant entity is the bacterium, not the person’s body becoming resistant. The consequence is reduced effectiveness of that antibiotic against an infection caused by those bacteria.

Susceptibility and resistance are relative to a particular drug or drug group. A strain resistant to antibiotic A is not automatically resistant to every other antibiotic. Nor does one susceptible strain establish that all bacteria of the same broad type will respond identically. Use the strain and antibiotic labels in a supplied table before predicting an effect.

Explain reduced effectiveness without claiming resistance to every drug

In a simplified model with susceptible and resistant bacteria exposed to antibiotic A, the susceptible group is killed while the resistant group survives. That contrast illustrates why an infection containing resistant bacteria may not be eliminated by A. It does not require the host to have repeatedly taken the drug: resistant bacteria can also be acquired through transmission.

A genuine laboratory susceptibility test needs standardised conditions and professional interpretation. The written course uses stated model identities and outcomes instead of asking learners to grow pathogens or handle antibiotics. Describe the resistance and reduced effectiveness using the supplied evidence; the Supplement lessons later explain changes in population proportions through selection and reproduction.

Pause and explain

If a strain is resistant to A, what follows about B?

Put the idea to work

Worked example

Strain R survives antibiotic A; strain S is killed. Describe the contrast.

Show the worked solution
  1. R is resistant to A under the stated conditions.
  2. S is susceptible to A.

Answer R is resistant to antibiotic A; S is susceptible to it. A is less effective against R.

Try a topic test

Choose Easy, Normal or Difficult. Save your answers and open worked review after finishing.

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From guided practice to a new situation

Write your answer and reasoning first. Use a hint only if you are stuck. The model solution is for self-checking; your written work is not automatically marked.

1 · Guided

Describe what antibiotic resistance means for a specified bacterial strain and drug.

Give me a hint

Include both survival or growth and reduced effectiveness.

Compare my reasoning
  1. The strain is not controlled as expected by that drug.
  2. It may survive or continue growing, reducing treatment effectiveness.

The bacterial strain can survive or continue growing despite the specified antibiotic, reducing that antibiotic’s effectiveness against it.

Look for these in your work

  • Assign resistance to bacteria
  • Connect survival with reduced effectiveness
2 · Independent

A kills strain S but not strain R. Classify both and state the implication for A.

Give me a hint

Use response to the same drug.

Compare my reasoning
  1. S is susceptible; R is resistant.
  2. A is less effective against R.

S is susceptible to A; R is resistant to A. A is less effective against R.

Look for these in your work

  • Classify both strains
  • State the drug-specific consequence
3 · Transfer

Correct: a person who has never taken A cannot acquire bacteria resistant to A, and all other antibiotics must also fail.

Give me a hint

Separate transmission and drug-specific response.

Compare my reasoning
  1. Resistant bacteria can be acquired through transmission.
  2. Response to other antibiotics needs separate evidence.

A person can acquire bacteria already resistant to A. Resistance to A alone does not establish resistance to every other antibiotic.

Look for these in your work

  • Allow transmitted resistance
  • Avoid unsupported all-drug claims

Common mistakes

  • Calling the patient’s body the resistant bacterium.
  • Assuming resistance to A means resistance to all antibiotics.
Recall without your notes

What can you explain now?

If a strain is resistant to A, what follows about B?

Compare with the explanation

Its response to B needs separate evidence

Resistance is drug-specific.

After trying it yourself, choose your next review. This is your self-assessment.

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Make it stick

Describe bacterial resistance and correct both the host-body and all-antibiotic misconceptions.

If you needed the solution, close it and solve the problem again from a blank page. A correct answer is stronger when you can explain the reason for each step.

Keep learning Biology

Course scope and assessment

780 sequenced lessons provide 2340 guided, independent and application problems in characteristics, classification, cells, organisation, specimen size, membrane transport, biological molecules, enzymes, plant and human nutrition, plant transport, circulatory systems, the heart, blood vessels, blood, disease transmission, body defences, immunity, gas exchange in humans, respiration energy uses and investigations, aerobic respiration, anaerobic respiration and recovery, excretion in humans, coordination and response, sense organs, hormones, homeostasis, tropic responses, drugs, asexual reproduction, sexual reproduction, sexual reproduction in plants, sexual reproduction in humans, sex hormones in humans, sexually transmitted infections, chromosomes, genes and proteins, mitosis, meiosis, monohybrid inheritance, variation, adaptive features, selection, energy flow, food chains and webs, nutrient cycles, population, community, ecosystem, population-growth phases, food supply, habitat destruction, pollution, conservation, biotechnology and genetic modification. 61 of 61 syllabus sections have linked teaching and staged practice. The earlier inheritance overview remains introductory, and the monohybrid pathway develops the relevant Core and Supplement requirements. This is not full programme completion or guaranteed exam readiness. Written practice is self-checked.

StudyForA · Learn with understanding

Original teaching content and links to official sources. Check your exam year and qualification before using a resource.