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IGCSE · Cambridge (CIE) · 0610

Describe mRNA passing through a ribosome

mRNA passes through the ribosome while a separate amino-acid chain is assembled. Counting completed stipulated passes can count model products; a passing message is not a moved chromosome.

Chromosomes, genes and proteins pathway · 17.1

Extended only (Supplement); Biology 0610, 2026–2028. Use the stated specimen features and evidence. Diagrams are schematic. Written practice is self-checked

Before you begin

  • Recall the nucleus, DNA base pairing, gametes, fertilisation, enzymes, membrane carriers and chemical synapses.

Work on paper. Try each question before revealing help, and explain why your method works.

Quick readiness check

What passes through the ribosome in the requirement?

What you will learn

  • Locate the message used in protein assembly
  • Separate the ribosome from the information source and product

Original teaching model. Counts and records are stipulated; drawings are schematic.

Describe mRNA passing through a ribosomemRNA passes through the ribosome while a separate amino-acid chain is assembled. Counting completed stipulated passes can count model products; a passing message is not a moved chromosome.NucleusDNA geneRemains heremRNA copyMade heremRNA moves to cytoplasmCytoplasmmRNABase orderRibosomeAmino acidsOrdered amino-acid chainmRNA bases determine product orderDNA and RNA are not the product material
mRNA passes through the ribosome while a separate amino-acid chain is assembled. Counting completed stipulated passes can count model products; a passing message is not a moved chromosome.
Information, material and count key
FeatureMeaning
Information moleculemRNA passes through ribosome
MachineryRibosome
Separate productGrowing amino-acid chain
Count conditionCompleted assembly events, not partial passes

Locate the message used in protein assembly

In the required protein-production sequence, mRNA passes through ribosomes. The ribosome is the assembly machinery using the message, not the DNA gene or the finished protein. The message’s base sequence carries the order information that guides assembly. The original nuclear gene remains at the source while the message is used in the cytoplasmic model.

A diagram can show a strand entering and leaving the ribosome with a growing amino-acid chain emerging separately. Label the strand mRNA and the growing chain protein or amino-acid chain. The two are different materials. A line passing through a ribosome is not automatically a chromosome, and the ribosome does not turn the message material into amino acids.

Separate the ribosome from the information source and product

One message can be used for more than one assembly event. If an original model stipulates three completed passes of the same message, each giving one chain, then it specifies three chain products under those conditions. Do not convert this limited event count into a rule that every message always makes exactly one protein or that incomplete passes count as completed products.

The original ribosome model is a schematic, not a measured molecular photograph. It shows the required message path and separate product material without detailed initiation, elongation or termination chemistry. The next lesson follows amino acids being assembled, so learners can explain both the information path and the material path.

Pause and explain

A model states three completed passes, each producing one chain. How many chains are specified?

Put the idea to work

Worked example

Which two labels distinguish the passing strand from the growing chain?

Show the worked solution
  1. Identify the message strand as mRNA.
  2. Identify the product chain as amino acids assembled into protein.

Answer mRNA passes through the ribosome; a separate amino-acid chain is assembled as the protein product.

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Choose Easy, Normal or Difficult. Save your answers and open worked review after finishing.

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From guided practice to a new situation

Write your answer and reasoning first. Use a hint only if you are stuck. The model solution is for self-checking; your written work is not automatically marked.

1 · Guided

Label the message passing through a ribosome and the separate growing product.

Give me a hint

Distinguish information molecule from assembled material.

Compare my reasoning
  1. Label the strand mRNA.
  2. Label the growing product amino-acid chain or protein.

The passing strand is mRNA; the separate growing product is an amino-acid chain forming a protein.

Look for these in your work

  • Name the message
  • Name the product material
2 · Independent

Count products in a stipulated model of three completed message passes, each giving one chain.

Give me a hint

Count completed assembly events.

Compare my reasoning
  1. Use three completed passes.
  2. Apply one chain per stated pass.

The model specifies three chain products; it does not establish a universal fixed number per mRNA molecule.

Look for these in your work

  • Use the completed event count
  • Keep the stipulation
3 · Transfer

A sketch shows four partial passes but no completed chains. Can it prove four finished proteins?

Give me a hint

Completion is part of the product-count condition.

Compare my reasoning
  1. Identify partial rather than completed events.
  2. Reject counting every partial event as a completed product.

No. Four partial passes do not establish four finished proteins; completion evidence has not been supplied.

Look for these in your work

  • Distinguish partial and complete
  • Reject unsupported product count

Common mistakes

  • The passing message is not the chromosome gene.
  • A message can support more than one assembly event.
Recall without your notes

What can you explain now?

A model states three completed passes, each producing one chain. How many chains are specified?

Compare with the explanation

Three under the stated conditions

Each completed event gives one stated product.

After trying it yourself, choose your next review. This is your self-assessment.

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Make it stick

Explain locate the message used in protein assembly and separate the ribosome from the information source and product. Use the stated cell, chromosome sets and information pathway before opening the solutions.

If you needed the solution, close it and solve the problem again from a blank page. A correct answer is stronger when you can explain the reason for each step.

Keep learning Biology

Course scope and assessment

780 sequenced lessons provide 2340 guided, independent and application problems in characteristics, classification, cells, organisation, specimen size, membrane transport, biological molecules, enzymes, plant and human nutrition, plant transport, circulatory systems, the heart, blood vessels, blood, disease transmission, body defences, immunity, gas exchange in humans, respiration energy uses and investigations, aerobic respiration, anaerobic respiration and recovery, excretion in humans, coordination and response, sense organs, hormones, homeostasis, tropic responses, drugs, asexual reproduction, sexual reproduction, sexual reproduction in plants, sexual reproduction in humans, sex hormones in humans, sexually transmitted infections, chromosomes, genes and proteins, mitosis, meiosis, monohybrid inheritance, variation, adaptive features, selection, energy flow, food chains and webs, nutrient cycles, population, community, ecosystem, population-growth phases, food supply, habitat destruction, pollution, conservation, biotechnology and genetic modification. 61 of 61 syllabus sections have linked teaching and staged practice. The earlier inheritance overview remains introductory, and the monohybrid pathway develops the relevant Core and Supplement requirements. This is not full programme completion or guaranteed exam readiness. Written practice is self-checked.

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