Learn in your language
Skip to content
IGCSE · Cambridge (CIE) · 0610

Describe cholera and its contaminated-water route

Identify a bacterial cause and trace an indirect route to a new host.

Disease and immunity pathway · 10.1

Extended only (Supplement); Biology 0610, 2026–2028. Use the stated specimen features and evidence. Diagrams are schematic. Written practice is self-checked

Before you begin

  • Recall indirect water transmission and disease-control measures.

Work on paper. Try each question before revealing help, and explain why your method works.

Quick readiness check

Which group contains the cholera pathogen?

What you will learn

  • Agent and vehicle are different
  • Link route control with the known agent
Bacterium in contaminated material → drinking water → new host. A symptom alone does not identify the agent.Describe cholera and itscontaminated-water routeAgentVibrio cholerae bacteriumVehicleContaminated waterTransferConsumption by anotherhost
Bacterium in contaminated material → drinking water → new host. A symptom alone does not identify the agent. Original teaching model.

WHO background: cholera cause and transmission. Original classroom questions; this model does not diagnose infection.

Agent and vehicle are different

Cholera is a disease caused by the bacterium Vibrio cholerae. Contaminated water can transmit the bacterium to another host when consumed. The water is the vehicle and the bacterium is the pathogen; neither a symptom such as diarrhoea nor the water itself is the causal organism.

In the required route, pathogen-containing faeces can contaminate a water source, then drinking that water brings bacteria into the digestive system. Contaminated food can also be a route, but the syllabus specifically requires the contaminated-water explanation. A clear-looking water sample does not establish absence of this bacterium.

Link route control with the known agent

A clean water supply and appropriate sewage treatment can reduce this faecal-contamination route. Explain where each measure interrupts the chain rather than claiming that water treatment makes the recipient produce antibodies or that every diarrhoeal illness must be cholera. The name of a symptom does not identify a particular pathogen.

This classroom sequence uses established biological mechanisms, with cholera’s toxin and osmotic effects taught next. It does not identify real infections from symptoms. The WHO source linked in the course materials supports the bacterial and contaminated-water description; original practice scenarios are invented and do not represent actual outbreak case records.

Pause and explain

Which chain explains the required cholera route?

Put the idea to work

Worked example

A supplied cholera route uses pathogen-containing water. Identify the causal agent and transmission vehicle.

Show the worked solution
  1. The agent is a bacterium.
  2. The vehicle is contaminated water.

Answer Agent: Vibrio cholerae bacterium. Vehicle: contaminated water.

Try a topic test

Choose Easy, Normal or Difficult. Save your answers and open worked review after finishing.

Test this topic →

From guided practice to a new situation

Write your answer and reasoning first. Use a hint only if you are stuck. The model solution is for self-checking; your written work is not automatically marked.

1 · Guided

Name the causal organism group and required transmission vehicle for cholera.

Give me a hint

Keep agent and vehicle separate.

Compare my reasoning
  1. Vibrio cholerae is a bacterium.
  2. It can reach a host in consumed contaminated water.

Bacterium; contaminated water.

Look for these in your work

  • Name the group
  • Name the vehicle
2 · Independent

Explain a sewage-to-host chain for the supplied cholera model.

Give me a hint

Trace contamination and ingestion.

Compare my reasoning
  1. Sewage contains pathogen-bearing faecal material.
  2. Water becomes contaminated and is swallowed by another host.

Pathogen-containing sewage → contaminated water → ingestion of the cholera bacterium by another host.

Look for these in your work

  • Include faecal contamination
  • Include consumption
3 · Transfer

An invented case lists diarrhoea but gives no identified organism or water-exposure evidence. Does it establish cholera?

Give me a hint

A symptom can have different causes.

Compare my reasoning
  1. Diarrhoea is not specific proof of this bacterium.
  2. The agent and route are not established.

No; the symptom alone does not establish cholera or its transmission route.

Look for these in your work

  • Avoid diagnosing from one symptom
  • Name missing evidence

Common mistakes

  • Calling diarrhoea the pathogen.
  • Inferring cholera from symptoms alone.
Recall without your notes

What can you explain now?

Which chain explains the required cholera route?

Compare with the explanation

Contaminated water is swallowed and carries the bacterium into a host

This is an indirect water route.

After trying it yourself, choose your next review. This is your self-assessment.

Your review choice appears on Today. Sign in to sync it across devices.

Make it stick

Trace the cholera route and mark two controls without calling water the pathogen.

If you needed the solution, close it and solve the problem again from a blank page. A correct answer is stronger when you can explain the reason for each step.

Keep learning Biology

Course scope and assessment

780 sequenced lessons provide 2340 guided, independent and application problems in characteristics, classification, cells, organisation, specimen size, membrane transport, biological molecules, enzymes, plant and human nutrition, plant transport, circulatory systems, the heart, blood vessels, blood, disease transmission, body defences, immunity, gas exchange in humans, respiration energy uses and investigations, aerobic respiration, anaerobic respiration and recovery, excretion in humans, coordination and response, sense organs, hormones, homeostasis, tropic responses, drugs, asexual reproduction, sexual reproduction, sexual reproduction in plants, sexual reproduction in humans, sex hormones in humans, sexually transmitted infections, chromosomes, genes and proteins, mitosis, meiosis, monohybrid inheritance, variation, adaptive features, selection, energy flow, food chains and webs, nutrient cycles, population, community, ecosystem, population-growth phases, food supply, habitat destruction, pollution, conservation, biotechnology and genetic modification. 61 of 61 syllabus sections have linked teaching and staged practice. The earlier inheritance overview remains introductory, and the monohybrid pathway develops the relevant Core and Supplement requirements. This is not full programme completion or guaranteed exam readiness. Written practice is self-checked.

StudyForA · Learn with understanding

Original teaching content and links to official sources. Check your exam year and qualification before using a resource.