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IGCSE · Cambridge (CIE) · 0610

Link red blood cells with oxygen transport

Connect haemoglobin and the mature mammalian cell model with a specialised role.

Cells and organisation pathway · 2.1

Core and Extended; Biology 0610, 2026–2028. Use the stated specimen features and evidence. Diagrams are schematic. Written practice is self-checked

Before you begin

  • Recall the distinction between plant, animal and bacterial cells. Read the supplied evidence before drawing a conclusion.

Work on paper. Try each question before revealing help, and explain why your method works.

What is the specified red-blood-cell role?

What you will learn

  • State the oxygen-transport function.
  • Explain why a specialised animal cell can lack a nucleus.
The mature mammalian red-cell model has haemoglobin and no nucleus. The biconcave centre is thinner, not an open hole. Other animal cells and vertebrate red cells can differ.A specialised oxygen-carryingcellThinner centre · not a holeMature mammalian red cellHaemoglobin: oxygen carriageNo nucleus in this model
The mature mammalian red-cell model has haemoglobin and no nucleus. The biconcave centre is thinner, not an open hole. Other animal cells and vertebrate red cells can differ.

An oxygen-carrying cell

Red blood cells transport oxygen using haemoglobin. In mammals, a mature red blood cell has a biconcave disc shape, a membrane and cytoplasm containing haemoglobin, but no nucleus. This leaves space for haemoglobin and is an exception to the typical animal-cell drawing.

The biconcave shape provides a large surface relative to volume and a short path to the interior; flexibility helps passage through narrow vessels. A red blood cell is not a hollow tube and does not pump blood: the heart provides the pumping action.

Qualify the model

The missing nucleus is a feature of mature mammalian red blood cells. It is not a rule for every animal cell or for every vertebrate red blood cell. The disc sketch is schematic; the pale centre represents a thinner region, not a hole.

Oxygen carriage and electrical-impulse conduction are different roles. Give the red-cell function precisely and connect haemoglobin to oxygen, rather than calling the cell a general messenger.

Why does a mature mammalian red cell not disprove the typical animal-cell comparison?

Put the idea to work

Worked example

A mature mammalian cell contains haemoglobin and lacks a nucleus. Name the cell and function.

Show the worked solution
  1. Haemoglobin supports oxygen carriage.
  2. This is the specialised mature red blood cell.

Answer Mature mammalian red blood cell; oxygen transport.

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Choose Easy, Normal or Difficult. Save your answers and open worked review after finishing.

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From guided practice to a new situation

Write your answer and reasoning first. Use a hint only if you are stuck. The model solution is for self-checking; your written work is not automatically marked.

1 · Guided

State the function of red blood cells and the protein involved.

Give me a hint

Link protein to transported gas.

Compare my reasoning
  1. Red cells transport oxygen.
  2. Haemoglobin supports carriage.

Oxygen transport using haemoglobin.

Look for these in your work

  • Both gas and protein.
  • Do not name chlorophyll.
2 · Independent

Explain why the pale centre of a biconcave red-cell sketch is not a hole.

Give me a hint

Biconcave describes thickness.

Compare my reasoning
  1. The central region is thinner.
  2. The membrane encloses continuous cell contents.

It is a thinner region of the disc, not an open hole.

Look for these in your work

  • Correct shape interpretation.
  • Retain cell continuity.
3 · Transfer

A student classifies any nucleus-free cell as a bacterium. Use a red-cell example to correct the rule.

Give me a hint

State the specialised exception precisely.

Compare my reasoning
  1. Mature mammalian red cells lack nuclei.
  2. They are specialised animal cells.
  3. Use combined structure and context, not one missing feature.

Nucleus absence alone is insufficient; mature mammalian red cells are animal cells.

Look for these in your work

  • Precise counterexample.
  • Combined evidence.

Common mistakes

  • The disc has a thinner centre, not a hole.
  • Qualify the no-nucleus statement to mature mammalian cells.
Recall without your notes

What can you explain now?

Which protein supports oxygen transport in red blood cells?

Compare with the explanation

Haemoglobin.

It binds oxygen for carriage in the blood.

After trying it yourself, choose your next review. This is your self-assessment.

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Make it stick

Explain oxygen transport and the limit of the typical-cell model.

If you needed the solution, close it and solve the problem again from a blank page. A correct answer is stronger when you can explain the reason for each step.

Keep learning Biology

Course scope and assessment

780 sequenced lessons provide 2340 guided, independent and application problems in characteristics, classification, cells, organisation, specimen size, membrane transport, biological molecules, enzymes, plant and human nutrition, plant transport, circulatory systems, the heart, blood vessels, blood, disease transmission, body defences, immunity, gas exchange in humans, respiration energy uses and investigations, aerobic respiration, anaerobic respiration and recovery, excretion in humans, coordination and response, sense organs, hormones, homeostasis, tropic responses, drugs, asexual reproduction, sexual reproduction, sexual reproduction in plants, sexual reproduction in humans, sex hormones in humans, sexually transmitted infections, chromosomes, genes and proteins, mitosis, meiosis, monohybrid inheritance, variation, adaptive features, selection, energy flow, food chains and webs, nutrient cycles, population, community, ecosystem, population-growth phases, food supply, habitat destruction, pollution, conservation, biotechnology and genetic modification. 61 of 61 syllabus sections have linked teaching and staged practice. The earlier inheritance overview remains introductory, and the monohybrid pathway develops the relevant Core and Supplement requirements. This is not full programme completion or guaranteed exam readiness. Written practice is self-checked.

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