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IGCSE · Cambridge (CIE) · 0610

Interpret a supplied insulin concentration response

Calculate the decrease in an invented glucose model without making a treatment decision.

Homeostasis pathway · 14.4

Core and Extended; Biology 0610, 2026–2028. Use the stated specimen features and evidence. Diagrams are schematic. Written practice is self-checked

Before you begin

  • Recall hormone production and blood transport, respiration, liver storage and electrical impulses along neurones.

Work on paper. Try each question before revealing help, and explain why your method works.

Quick readiness check

Which direction is shown by 8→6 model units?

What you will learn

  • Read the supplied concentration values
  • Calculate absolute and percentage decreases

Interpret a supplied insulin concentration response

Invented insulin-response concentration model: 8→6 units, a 2-unit or 25% decrease. It is not a personal dosing record. Original teaching model.

Homeostasis model reference
FeatureMeaning
Before8 model units
After6 model units
Decrease2 model units; 25%
ScopeEducational concentration model, not treatment dosing

Read the supplied concentration values

The supplied teaching model shows blood glucose concentration changing from 8 to 6 model units during an insulin response. The values are invented and do not use a clinical diagnostic range. The change direction is downward, matching the Core statement that insulin decreases blood glucose concentration. The record measures concentration rather than insulin quantity or blood volume.

Calculate the absolute decrease as the starting value minus the later value: 8 − 6 = 2 model units. A signed change written as later minus earlier would be −2 model units; the negative sign indicates a decrease. State which convention you use so a decrease magnitude is not mistaken for an increase.

Calculate absolute and percentage decreases

Percentage decrease compares the decrease with the starting value. Here, 2/8 × 100 = 25%. Dividing by the later value would answer a different comparison and would not give percentage decrease from the baseline. A second supplied model changing from 10 to 7.5 units also has a 25% decrease, despite a different absolute decrease.

The supplied insulin-response model supports the effect direction and calculations. A real uncontrolled before-and-after record would not by itself prove a sole hormonal cause. These invented values cannot be turned into a clinical insulin dose, because no personal care plan or dosing relationship is provided. Interpret the stated educational model within its stated scope.

Pause and explain

What percentage decrease is 8→6?

Put the idea to work

Worked example

Calculate the decrease from 8 to 6 model units.

Show the worked solution
  1. Decrease magnitude is 8 − 6 = 2 model units.
  2. Percentage decrease is 2/8 × 100 = 25%.

Answer 2 model units decrease; 25% decrease.

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Choose Easy, Normal or Difficult. Save your answers and open worked review after finishing.

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From guided practice to a new situation

Write your answer and reasoning first. Use a hint only if you are stuck. The model solution is for self-checking; your written work is not automatically marked.

1 · Guided

Calculate the absolute and percentage decrease in the displayed model.

Give me a hint

Use the starting concentration for the denominator.

Compare my reasoning
  1. 8 − 6 = 2 model units.
  2. 2/8 × 100 = 25%.

Decrease: 2 model units, or 25%.

Look for these in your work

  • Calculate the absolute decrease
  • Use the baseline percentage
2 · Independent

A second model changes from 10 to 7.5 units. Calculate its decrease magnitude and percentage.

Give me a hint

Compare 2.5 with the starting 10.

Compare my reasoning
  1. 10 − 7.5 = 2.5 model units.
  2. 2.5/10 × 100 = 25%.

Decrease: 2.5 model units, or 25%.

Look for these in your work

  • Use the second baseline
  • Distinguish absolute and relative changes
3 · Transfer

Why do the two 25% decreases not mean equal absolute changes or a usable insulin dose?

Give me a hint

Compare baselines and the information actually supplied.

Compare my reasoning
  1. Absolute changes differ because the starting values differ.
  2. No personal dosing relationship is supplied.

The absolute decreases are 2 and 2.5 model units because the baselines differ. Neither model supplies an insulin dose or personal care plan.

Look for these in your work

  • Distinguish proportional and absolute change
  • Keep the model separate from treatment

Common mistakes

  • Dividing by the later value.
  • Turning invented model units into an insulin dose.
Recall without your notes

What can you explain now?

What percentage decrease is 8→6?

Compare with the explanation

25%

Use (8−6)/8 × 100.

After trying it yourself, choose your next review. This is your self-assessment.

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Make it stick

Calculate a concentration decrease and explain the limits of invented model values.

If you needed the solution, close it and solve the problem again from a blank page. A correct answer is stronger when you can explain the reason for each step.

Keep learning Biology

Course scope and assessment

780 sequenced lessons provide 2340 guided, independent and application problems in characteristics, classification, cells, organisation, specimen size, membrane transport, biological molecules, enzymes, plant and human nutrition, plant transport, circulatory systems, the heart, blood vessels, blood, disease transmission, body defences, immunity, gas exchange in humans, respiration energy uses and investigations, aerobic respiration, anaerobic respiration and recovery, excretion in humans, coordination and response, sense organs, hormones, homeostasis, tropic responses, drugs, asexual reproduction, sexual reproduction, sexual reproduction in plants, sexual reproduction in humans, sex hormones in humans, sexually transmitted infections, chromosomes, genes and proteins, mitosis, meiosis, monohybrid inheritance, variation, adaptive features, selection, energy flow, food chains and webs, nutrient cycles, population, community, ecosystem, population-growth phases, food supply, habitat destruction, pollution, conservation, biotechnology and genetic modification. 61 of 61 syllabus sections have linked teaching and staged practice. The earlier inheritance overview remains introductory, and the monohybrid pathway develops the relevant Core and Supplement requirements. This is not full programme completion or guaranteed exam readiness. Written practice is self-checked.

StudyForA · Learn with understanding

Original teaching content and links to official sources. Check your exam year and qualification before using a resource.